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ProteomicsCognitive Decline in Older Adults with Type 2 Diabetes: Unraveling Site-Specific Glycoproteomic Alterations
Type 2 diabetes (T2D) is consistently associated with an elevated risk of cognitive decline and dementia. The underlying molecular mechanisms relating T2D to cognitive decline remain unclear, impeding the ability to detect the earliest stages of cognitive decline in older adults with T2D, consequent...
ORGANISM(S): Homo sapiens (Human) 
2025-02-16 | PXD050780 | Pride
Glycosylation Glycation Serum Glycoproteomics Plasma Cognition 
GenomicGenetics Consortium for Late Onset of Alzheimer's Disease (LOAD CIDR Project)

Multiplex Family Study
The purpose of the NIA Genetics Initiative: Multiplex Family Study is to identify families with multiple members diagnosed with late-onset Alzheimer's Disease. Families will be characterized clinically and blood samples will be collected to establish cell...

phs000160 | dbGaP
GenomicNIA - Late Onset Alzheimer's Disease and National Cell Repository for Alzheimer's Disease Family Study: Genome-Wide Association Study for Susceptibility Loci

Alzheimer disease is the most common neurodegenerative disorder of the elderly affecting an estimated five million Americans. Genetic factors contribute to the risk for disease with heritability estimates ranging from 57% to 79%. More than a decade ago, the ε4 variant of APOE was identified ...

phs000168 | dbGaP
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