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Alternative cleavage and polyadenylation (APA) generates diverse mRNA isoforms. We developed 3' region extraction and deep sequencing (3'READS) to address mispriming issues that commonly plague poly(A) site (pA) identification, and we used the method to comprehensively map pAs in the mouse genome. T...
ORGANISM(S): Mus musculus 
To reveal the scope of the Spx regulation and explore the differences in the regulatory roles of SpxA1 and SpxA2, the global gene transcription profiles of the WT, M-bM-^HM-^FspxA1 and M-bM-^HM-^FspxA2 strains were determined by DNA microarray analysis performed using an Agilent custom-designed olig...
ORGANISM(S): Streptococcus suis 
Covalent inhibitors have recently seen a resurgence of interest in drug development. Nevertheless, compounds, that do not rely on an enzymatic activity, have almost exclusively been developed to target cysteines. Expanding the scope to other amino acids would be largely facilitated by the ability to...
ORGANISM(S): Escherichia coli Staphylococcus aureus 
2020-04-14 | PXD016659 | Pride
Mycobacterium canetti strain:NLA000701671 Genome sequencing
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