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In vitro experiment of stimulation of monocyte-derived dendritic cells with Saccaromyces cerevisiae in exponential growth phase. This experiment was performed to verify the comparability of microarray experiments using a pathway based logic (Beltrame et al., PLoS 2009) by comparing the analysis of t...
ORGANISM(S): Homo sapiens 
Various studies showed a significant production/release of IL-1 beta following status epilepticus (SE) and during epileptogenesis. We studied the role of this cytokine in the epileptogenic process by blocking its production and downstream effects in vivo in a model of acquired epilepsy following SE ...
ORGANISM(S): Rattus norvegicus 
In order to study the effects of trabectedin in chronic myelomonocytic leukemia and in juvenile myelomonocytic leukemia, we performed whole genome transcriptional profiling of a model cell line treated under either the reference drug for CMML / JMML (Azacitidine) or trabectedin.
ORGANISM(S): Homo sapiens 
Human T cell clones were derived according to standard protocols using different mix of cytokines, once assessed for their functional profile were studied for gene expression. The purpose of this study is to analyze human Th1 and Th17 clones with and without stimulation with PMA and Ionomycin to mea...
ORGANISM(S): Homo sapiens 
Various studies have shown that aerobic exercise can prevent or alleviate cancer-induced muscle wasting. To reproduce at least partially in vitro some molecular differences of aerobic muscle exercise that are independent from systemic inflammation or the hormonal milieu, we infected fully different...
ORGANISM(S): Mus musculus 
Human monocyte derived dendritic cells were exposed to the pure Dectin-1 agonist Curdlan to analyze the early transcriptional activation of DCs. This experiment is related to E-MTAB-750.
ORGANISM(S): Homo sapiens 
In order to dissect the response from different fungal cell wall components, monocyte-derived dendritic cells obtained from healthy donors were collected and either left untreated, or treated for four hours with either mannan, zymosan, curdlan, whole yeast, or yeast spores. This experiment is relat...
ORGANISM(S): Homo sapiens 
Monocyte-derived dendritic cells obtained from healthy donors were collected and either left untreated, or treated for three hours with heat-killed Candida albicans. Three distinct donors were used. Related data sets have been deposited in ArrayExpress under accessions E-MTAB-750 and E-MTAB-1213
ORGANISM(S): Homo sapiens 
In the last decades platinum-based neo-adjuvant chemotherapy (NACT) has been recognized as a reliable therapeutic strategy in patients with un-resectable advanced epithelial ovarian cancer (EOC). However, the molecular changes induced by NACT at miRNA level, and their prognostic role has not been cl...
ORGANISM(S): Homo sapiens 
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