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Benzene is a ubiquitous environmental contaminant and is widely used in industry. Exposure to benzene causes a number of serious health problems, including blood disorders and leukemia. Benzene undergoes complex metabolism in humans, making mechanistic determination of benzene toxicity difficult. We...
ORGANISM(S): Saccharomyces cerevisiae 
There is increasing concern regarding the adverse effects of air pollution on human health, and benzene is a major toxic compound in air pollution. Maternal benzene exposure has been associated with reproductive complications, such as preterm birth, low birth weight, and immunological and neurologic...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD035085 | Pride
Benzene is known to be a common toxic industrial chemical, and prolonged benzene exposure may cause nervous system damage. At present, there were few studies on benzene-induced neurological damage. This research aimed to identify protein biomarkers to predict central nervous system damage of benzene...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD046028 | Pride
Benzene is a ubiquitous environmental pollutant and an established human hematotoxicant and leukemogen. New insights into the pathogenesis of benzene hematotoxicity are urgently needed. Long non-coding RNA(lncRNA)can regulate gene expression and widely participate in the various physiological and pa...
ORGANISM(S): Homo sapiens 
Benzene, a natural component of petroleum products, is a known hematotoxic and leukemogenic agent. The haematotoxic effect and excess leukemia has been reported below 1 ppm, an exposure level previously considered not to cause any health effects. Gene expression studies suggest that benzene affects ...
ORGANISM(S): Homo sapiens 
Chronic Benzene Exposure Aggravates Pressure Overload-Induced Cardiac Dysfunction
au12-01_detox; Improving the knowledge of the metabolic pathways of benzene in higher plants Cabbages (Brassica oleracea Var. Prover)are directly submitted to a one dose of benzene (3ppm) during 1 hour or 3 hours. The comparison is realized between samples treated and untreated to the benzene for bo...
ORGANISM(S): Brassica oleracea 

The widespread use of agricultural plastic films has made micro- and nanoplastics (MNPs) and phthalate esters (PAEs) contaminants of emerging concern in agroecosystems. However, the interactive mechanisms underlying their combined pollution in soil-plant systems remain elusive. To fill this gap, ...

2025-08-22 | MTBLS12878 | MetaboLights
The present research aimed to study the interaction of three chemicals, methyl mercury, benzene and trichloroethylene, on mRNA expression alterations in rat liver and kidney measured by microarray analysis. These compounds were selected on presumed different modes of action. The chemicals were admi...
ORGANISM(S): Rattus norvegicus 
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