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TranscriptomicsA library of yeast transcription factor motifs
The sequence specificity of DNA-binding proteins is the primary mechanism by which the cell recognizes genomic features. Here, we describe systematic determination of yeast transcription factor DNA-binding specificities. We obtained binding specificities for 112 DNA-binding proteins representing 19 ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-12-26 | E-GEOD-12349 | biostudies-arrayexpress
TranscriptomicsMLL1 is essential for the senescence-associated secretory phenotype [RNA-Seq]
Oncogene-induced senescence (OIS) and therapy-induced senescence (TIS), while tumor-suppressive, also promote procarcinogenic effects by activating the DNA damage response (DDR), which in turn induces inflammation. This inflammatory response prominently includes an array of cytokines known as the se...
ORGANISM(S): Homo sapiens 
2016-02-23 | E-GEOD-78138 | biostudies-arrayexpress
TranscriptomicsChromatin Immunoprecipitation microarray data from antiHA IP in stable LNCaP cells expressing either YFP or HA-SOX4/YFP
SOX4 is a critical developmental transcription factor in vertebrates and is required for precise differentiation and proliferation in multiple tissues. In addition, SOX4 is overexpressed in many human malignancies, but the precise role of SOX4 in cancer progression is not well understood. He...
ORGANISM(S): Homo sapiens 
2008-11-09 | E-GEOD-11874 | biostudies-arrayexpress
GenomicsMLL1 is essential for the senescence-associated secretory phenotype [ChIP-Seq]
Oncogene-induced senescence (OIS) and therapy-induced senescence (TIS), while tumor-suppressive, also promote procarcinogenic effects by activating the DNA damage response (DDR), which in turn induces inflammation. This inflammatory response prominently includes an array of cytokines known as the se...
ORGANISM(S): Homo sapiens 
2016-02-23 | E-GEOD-78141 | biostudies-arrayexpress
UnknownLeveraging Systematic Functional Analysis to Benchmark an In Silico Framework Distinguishes Driver from Passenger MEK Mutants in Cancer.
Not available
S-EPMC7541597 | biostudies-literature
TranscriptomicsPatient glioma microarray for Impaired histone demethylation contributes to the cell differentiation arrest induced by cancer-associated isocitrate dehydrogenase mutation
To study the effects of IDH mutations, we collected and performed gene expression microarray analysis with tumor specimens from patients with grade II-III oligodendroglioma. Sequencing for mutations of IDH1 and IDH2 was done. Gene expression was compared between IDH wildtype vs. mutant samples
ORGANISM(S): Homo sapiens 
2012-02-01 | E-MEXP-3239 | biostudies-arrayexpress
UnknownSurvival After Invasive or Conservative Management of Stable Coronary Disease.
Not available
S-EPMC9797439 | biostudies-literature
UnknownSex Differences in Revascularization, Treatment Goals, and Outcomes of Patients With Chronic Coronary Disease: Insights From the ISCHEMIA Trial.
Not available
S-EPMC10944079 | biostudies-literature
UnknownEvaluating the Appropriate Use Criteria for Coronary Revascularization in Stable Ischemic Heart Disease Using Randomized Data From the ISCHEMIA Trial.
Not available
S-EPMC11919559 | biostudies-literature
UnknownHealth Status Outcomes With Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting in ISCHEMIA.
Not available
S-EPMC12492304 | biostudies-literature
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