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TranscriptomicsTranscription profiling of Arabidopsis defective in the expression of TGA2, TGA5, and TGA6
12-oxo-phytodienoic acid (OPDA) and phytoprostane A1 (PPA1) are cyclopentenone oxylipins that are formed via the enzymatic; jasmonate pathway and a nonenzymatic, free radical–catalyzed pathway, respectively. Both types of cyclopentenone oxylipins; induce the expression of genes related to detoxifi...
ORGANISM(S): Arabidopsis thaliana 
2008-06-18 | E-GEOD-10732 | biostudies-arrayexpress
TranscriptomicsResponse of Arabidopsis cell culture to phytoprostane A1
12-Oxo-phytodienoic acid (OPDA) and several phytoprostanes are structurally related cyclopentenone oxylipins that can be formed via the enzymatic jasmonate pathway and a non-enzymatic, free radical-catalyzed pathway, respectively. To elucidate the biological activities of phytoprostanes in compariso...
ORGANISM(S): Arabidopsis thaliana 
2008-06-18 | E-GEOD-10719 | biostudies-arrayexpress
UnknownQuantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo.
Not available
S-EPMC2040481 | biostudies-literature
TranscriptomicsThe molecular phenotype of endocapillary proliferation in IgA nephropathy and potential modulation by bioactive small molecules
Endocapillary proliferation is associated with higher risk of progressive disease in IgAN. To better understand molecular pathways involved in the development of endocapillary proliferation and to identify novel specific therapeutic targets, we evaluated the glomerular transcriptome of microdissecte...
ORGANISM(S): Homo sapiens 
2015-05-18 | E-GEOD-50469 | biostudies-arrayexpress
TranscriptomicsEffect of Mineralocorticoid Receptor deletion on glucocorticoid signalling in the macropahge
Inappropriate excess of the steroid hormone aldosterone, which is a mineralocorticoid receptor (MR) agonist, is associated with increased inflammation and risk of cardiovascular disease. MR antagonists are cardioprotective and antiinflammatory in vivo, and evidence suggests that they mediate these e...
ORGANISM(S): Mus musculus 
2010-07-30 | E-GEOD-23308 | biostudies-arrayexpress
UnknownExpression of the Immune Checkpoint Protein VISTA Is Differentially Regulated by the TGF-β1 - Smad3 Signaling Pathway in Rapidly Proliferating Human Cells and T Lymphocytes.
Not available
S-EPMC8866318 | biostudies-literature
TranscriptomicsEvaluation of methods for modeling transcription factor sequence specificity
Genomic analyses often involve scanning for potential transcription-factor (TF) binding sites using models of the sequence specificity of DNA binding proteins. Many approaches have been developed to model and learn a protein’s binding specificity by representing sequence motifs, including the gaps a...
ORGANISM(S): synthetic construct 
2012-12-13 | E-GEOD-42864 | biostudies-arrayexpress
TranscriptomicsCHAC1 mRNA expression is a strong prognostic biomarker in breast and ovarian cancer
Extracellular, cancer-specific methylated DNA has been shown to be a prognostic marker when detected in serum or plasma. In this study we investigated the effect of treating cancer cells with differentially methylated CpG DNA. When breast cancer cell lines were treated with methylated CpG DNA, a con...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-22865 | biostudies-arrayexpress
ProteomicsImpact of CD74 knockdown on the HLA peptidome of the H1 melanoma cell line
The influence of CD74 expression on the HLA peptidome of the H1 melanoma cell line was analyzed by label-free quantitation mass spectrometry of HLA ligand extracts obtained from CD74 siRNA & control siRNA treated cells.
ORGANISM(S): Homo sapiens (Human) 
2018-03-01 | PXD008937 | Pride
Hla peptidome Melanoma Cd74 
TranscriptomicsTranslocations Activating IRF4 Identify a Subtype of Germinal-Center-Derived B-cell Lymphoma Affecting Predominantly Children and Young Adults
Background: Germinal center B-cell (GCB) lymphomas are common in children and adults. The prognosis strongly depends on age. Subgroups of GCB-lymphomas are characterized by chromosomal translocations affecting immunoglobulin (IG) loci leading to oncogene deregulation. Methods: Novel IG translocation...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-22470 | biostudies-arrayexpress
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