Sort   by:  
 Page size 
TranscriptomicsTranscriptomic and proteomic profiling reveal insights of mesangial cell function in patients with IgA Nephropathy
IgA nephropathy (IgAN) is the most common glomerulonephritis in the world. The disease is characterized by galactose deficient IgA (gd-IgA) in the circulation forming immune complexes. The complexes are deposited in the glomerular mesangium leading to inflammation and loss of renal function, but the...
ORGANISM(S): Homo sapiens 
2017-07-03 | E-GEOD-93798 | biostudies-arrayexpress
TranscriptomicsHuman and mouse lupus nephritis cross-species transcriptional analysis
This SuperSeries is composed of the following subset Series: GSE32583: Expression data from lupus NZB/W, NZM2410, NZW/BXSB mouse kidneys prenephritic and nephritic. GSE32591: Expression data from human with lupus nephritis (LN) Refer to individual Series
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-32592 | biostudies-arrayexpress
TranscriptomicsExpression data from human healthy CD133+ bone marrow EPCs
Systemic lupus erythematosus (SLE) is characterized by increased vascular risk due to premature atherosclerosis independent of traditional risk factors. We previously proposed that interferon-α plays a crucial role in premature vascular damage in SLE. IFN-α alters the balance between endothelial cel...
ORGANISM(S): Homo sapiens 
2011-04-13 | E-GEOD-26951 | biostudies-arrayexpress
TranscriptomicsExpression data from human healthy EPCs/CACs
Systemic lupus erythematosus (SLE) is characterized by increased vascular risk due to premature atherosclerosis independent of traditional risk factors. We previously proposed that interferon-? plays a crucial role in premature vascular damage in SLE. IFN-? alters the balance between endothelial cel...
ORGANISM(S): Homo sapiens 
2011-04-13 | E-GEOD-26949 | biostudies-arrayexpress
TranscriptomicsExpression data from human healthy and lupus EPCs/CACs, and healthy CD133+ bone marrow EPCs
Systemic lupus erythematosus (SLE) is characterized by increased vascular risk due to premature atherosclerosis independent of traditional risk factors. We previously proposed that interferon-α plays a crucial role in premature vascular damage in SLE. IFN-α alters the balance between endothelial cel...
ORGANISM(S): Homo sapiens 
2011-04-13 | E-GEOD-23203 | biostudies-arrayexpress
TranscriptomicsExpression data from human lupus EPCs/CACs
Systemic lupus erythematosus (SLE) is characterized by increased vascular risk due to premature atherosclerosis independent of traditional risk factors. We previously proposed that interferon-α plays a crucial role in premature vascular damage in SLE. IFN-α alters the balance between endothelial cel...
ORGANISM(S): Homo sapiens 
2011-04-13 | E-GEOD-26950 | biostudies-arrayexpress
TranscriptomicsTissue Transcriptome Driven Identification of Epidermal Growth Factor as a Chronic Kidney Disease Biomarker
We identified EGF as the top candidates predicting kidney function through an intrarenal transcriptome-driven approach, and demonstrated it is an independent risk predictor of CKD progression and can significantly improve prediction of renal outcome by established clinical parameters in diverse popu...
ORGANISM(S): Homo sapiens 
2015-12-14 | E-GEOD-69438 | biostudies-arrayexpress
TranscriptomicsThe molecular phenotype of endocapillary proliferation in IgA nephropathy and potential modulation by bioactive small molecules
Endocapillary proliferation is associated with higher risk of progressive disease in IgAN. To better understand molecular pathways involved in the development of endocapillary proliferation and to identify novel specific therapeutic targets, we evaluated the glomerular transcriptome of microdissecte...
ORGANISM(S): Homo sapiens 
2015-05-18 | E-GEOD-50469 | biostudies-arrayexpress
UnknownEpidermal Interferon-κ Drives Cutaneous Lupus-Like Lesions, Photosensitivity, and Systemic Autoimmunity In Vivo.
Not available
S-EPMC12854000 | biostudies-literature
TranscriptomicsCross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritis [Glomeruli]
Expression data from human with IgA nephropathy (IgAN) and hypertensive nephropathy (HT) We used microarrays to analyze the transcriptome of microdissected renal biopsies from patients with IgAN and HT RNA from glomeruli and tubulointerstitial compartments was extracted and processed for hybridizati...
ORGANISM(S): Homo sapiens 
2012-12-10 | E-GEOD-37460 | biostudies-arrayexpress
Sort   by:  
 Page size