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TranscriptomicsBarley host response to the direct application of the trichothecene mycotoxin deoxynivalenol
Barley florets (cv. Morex) were treated with 2.0 microgram deoxynivalenol per floret via a 10 microliter solution or mock inoculated with water. Samples were collected at 1, 12, 24, and 48 hours after inoculation. ****[PLEXdb(http://www.plexdb.org) has submitted this series at GEO on behalf of the...
ORGANISM(S): Hordeum vulgare 
2011-11-22 | E-GEOD-33405 | biostudies-arrayexpress
TranscriptomicsInhibitors that block initiation of wall teichoic acid biosynthesis sensitize methicillin-resistant Staphylococcus aureus to beta-lactams
Methicillin resistance in Staphylococcus aureus depends on the production of mecA, which encodes penicillin-binding protein 2A (PBP2A), an acquired peptidoglycan transpeptidase with reduced susceptibility to beta-lactam antibiotics. Here, we show that preventing the expression of wall teichoic acids...
ORGANISM(S): Staphylococcus aureus 
2010-10-19 | E-GEOD-24439 | biostudies-arrayexpress
TranscriptomicsSBV - Gene Expression Profiles of Lung Cancer Tumors - Adenocarcinomas and Squamous Cell Carcinomas
This dataset encompassing the profiles of 150 lung cancer tumors was developed to serve as test dataset in the SBV IMPROVER Diagnostic Signature Challenge (sbvimprover.com). The aim of this subchallenge was to verify that it is possible to extract a robust diagnostic signature from gene expression d...
ORGANISM(S): Homo sapiens 
2013-10-18 | E-GEOD-43580 | biostudies-arrayexpress
Transcriptomicsovation-Transcriptomic study of rice seed ageing
affy_rice_2012_01 - ovation - One of the key questions for future agriculture will be to save agronomical relevant biodiversity. To do so, it is important to select the best crop cultivars that will germinate efficiently (good seed vigor) and for a long period of time (good seed longevity). Surprisi...
ORGANISM(S): Oryza sativa 
2013-09-01 | E-GEOD-46334 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human THP-1 cells in response to treatment with lipo-polysaccharide for 1 or 4 hours
Effect of LPS in a time dependent manner (1hr or 4hr treatment v untreated) on the THP-1 cell using a focused microarray containing 465 putative or known NF-kappaB regulated genes.
ORGANISM(S): Homo sapiens 
2006-09-29 | E-MEXP-868 | biostudies-arrayexpress
Transcriptomicsivt-Transcriptomic study of rice seed ageing
affy_rice_2012_01 - ivt - One of the key questions for future agriculture will be to save agronomical relevant biodiversity. To do so, it is important to select the best crop cultivars that will germinate efficiently (good seed vigor) and for a long period of time (good seed longevity). Surprisingly...
ORGANISM(S): Oryza sativa 
2013-09-01 | E-GEOD-46342 | biostudies-arrayexpress
TranscriptomicsSingle-nucleus RNA-seq (10x Genomics Flex) of wild-type C57BL/6J mouse spleen following Plasmodium berghei ANKA infection, generated as a transcriptome-wide reference for the SpatialBench spatial transcriptomics benchmark
This dataset provides single-nucleus RNA-sequencing (snRNA-seq) profiles of wild-type mouse spleen, generated as a matched, transcriptome-wide reference for the SpatialBench resource benchmarking high-resolution spatial transcriptomics platforms (Visium HD, Xenium and MERSCOPE). Spleens were collect...
ORGANISM(S): Mus musculus 
2026-07-07 | E-MTAB-17245 | biostudies-arrayexpress
GenomicsEssential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma
Malignant melanoma is an aggressive cancer known for its notorious resistance to most current therapies. The basic helix-loop-helix microphthalmia transcription factor (MITF) is the master regulator determining the identity and properties of the melanocyte lineage, and is regarded as a lineage-speci...
ORGANISM(S): Homo sapiens 
2014-12-13 | E-GEOD-64137 | biostudies-arrayexpress
ProteomicsCritical Assessment of Metaproteome Investigation (CAMPI): a Multi-Lab Comparison of Established Workflows
Metaproteomics, the study of the collective proteome within a microbial ecosystem, has substantially grown over the past few years. This growth comes from the increased awareness that it can powerfully supplement metagenomics and metatranscriptomics analyses. Although metaproteomics is more challeng...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) Homo Sapiens (ncbitaxon:9606) 
2022-06-08 | MSV000089620 | MassIVE
ProteomicsProteomics Indicates Lactate Dehydrogenase is Prognostic in Acetaminophen-induced Acute Liver Failure Patients and Reveals a Role for LKB1-AMPK Signaling
Better biomarkers to predict death early in acute liver failure (ALF) are needed. To that end, we obtained early (study day 1) and later (day 3) serum samples from transplant-free survivors (n=28) and non-survivors (n=30) of acetaminophen (APAP)-induced ALF from the NIH-sponsored Acute Liver Failure...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD029576 | Pride
Liver regeneration Acute liver injury Drug-induced liver injury Biomarkers 
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