Sort   by:  
 Page size 
MetabolomicsMetabolic profiling of ob/ob mouse fatty liver using HR-MAS 1H-NMR combined with gene expression analysis reveals alterations in betaine metabolism and the transsulfuration pathway
Metabolic perturbations resulting from excessive hepatic fat accumulation are poorly understood. Thus, in this study, leptin-deficient ob/ob mice, a mouse model of fatty liver disease, were used to investigate metabolic alterations in more detail. Metabolites were quantified in intact liver tissues ...
2018-01-31 | MTBLS400 | MetaboLights
TranscriptomicsThe effects of UVB and the organic osmolyte betaine on rat epidermal keratinocytes in an organotypic culture system
Betaine (trimethylglycine) is a non-toxic, highly water-soluble organic osmolyte widely used in skin care due to its assumed moisturizing and protective properties, but only few studies have addressed its specific effects in skin. Here, the cellular and molecular targets of betaine were analyzed by ...
ORGANISM(S): Rattus norvegicus 
2015-10-26 | E-GEOD-63004 | biostudies-arrayexpress
MetabolomicsGlycine betaine uptake and metabolism in marine microbial communities
Not available
ORGANISM(S): Natural mixed marine microbial community 
ST002008 | MetabolomicsWorkbench
ProteomicsAlterations in Bacillus subtilis caused by high salinity and the compatible solute glycine betaine
Cells were grown aerobically at 37 degC in Spizizen minimal medium either supplemented with 1 mM glycine betaine, 1.2 M NaCl or 1.2 M NaCl and 1 mM glycine betaine. Cells were harvested in the exponential growth phase at an OD600nm of 1.0. Proteome analysis was performed with samples from three biol...
ORGANISM(S): Bacillus Subtilis (ncbitaxon:1423) 
2020-01-08 | MSV000084766 | MassIVE
ProteomicsHuman squamous cell carcinoma HSC-4 betaine treatment
This study aims to examine the effects of betaine on the survival, proliferation, and invasion of human oral squamous carcinoma cells (HSC) and further elucidate the potential function of betaine via the utilisation of proteomic analysis.
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD054595 | Pride
Betaine Squamous cell carcinoma 
MetabolomicsAnalysis the concentration of betaine, choline, TMA, TMAO and amino acids in plasma in Megalobrama amblycephala.
Not available
ORGANISM(S): Megalobrama amblycephala 
ST000982 | MetabolomicsWorkbench
MetabolomicsMetabolite and gene expression profiles suggest a putative mechanism through which high dietary carbohydrates reduce the content of hepatic betaine in Megalobrama amblycephala
Not available
ORGANISM(S): Megalobrama amblycephala 
ST000966 | MetabolomicsWorkbench
ProteomicsProteome of proline betaine-grown Eubacterium limosum ATCC 8486
Proline betaine, and to a much lesser extent, N-methyl L-proline, are found in citrus fruits and often present in the human metabolome. However, most of the N-methyl L-proline found in an animal model metabolome is produced by the microbiota, yet organisms and enzymes capable of producing N-methyl p...
ORGANISM(S): Eubacterium limosum Bacteria 
2019-07-25 | PXD013962 | Pride
Human gut isolate Acetogenic bacteria Proline betaine N-methyl proline 
TranscriptomicsGene regulation in Bacillus subtilis by the compatible solute glycine betaine
Glycine betaine (GB) is a potent osmoprotectant for salt stressed Bacillus subtilis cells, which possess three high-affinity uptake systems for GB. OpuA is the dominant transporter for this compatible solute. Northern blot analysis, primer extension experiments and opuA-treA reporter gene fusion stu...
ORGANISM(S): Bacillus subtilis 
2010-05-15 | E-GEOD-17435 | biostudies-arrayexpress
Genomicsglycine betaine degradation by salt marsh microbial community
We studied degradation of glycine betaine by salt marsh microbes and the formation of trimethylamine and methane from glycine betaine
PRJEB28840 | ENA
Sort   by:  
 Page size