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TranscriptomicsLineage-dependent spatial and functional organisation of the mammalian enteric nervous system
Single-cell transcriptomic analysis to delineate key regulators of neurogenic commitment in the enteric nervous system. To resolve the molecular profiles of ENCCs and identify transcriptional signatures of lineage restriction and differentiation, we analyzed their transcriptomes by single-cell RNA-s...
ORGANISM(S): Mus musculus 
2020-07-27 | E-MTAB-5553 | biostudies-arrayexpress
TranscriptomicsHigh-resolution analysis of gene activity during the Xenopus mid-blastula transition
The Xenopus mid-blastula transition (MBT) marks the onset of large-scale zygotic transcription, as well as an increase in cell cycle length and a loss of synchronous cell divisions. Little is known about what triggers the activation of transcription or how newly expressed genes interact with each ot...
ORGANISM(S): Xenopus (Silurana) tropicalis 
2014-03-27 | E-GEOD-56242 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of Lgr6 positive and negative cells in mouse mammary gland
Lgr6-positive cells have been shown to label stem/progenitors cells in several tissues including tongue and skin. However their role in mammary gland has never been investigated. Here we used Lgr6-eGFP-IRES-CreER2 mice to isolate and characterize Lgr6-positive population in mammary gland of 5-week o...
ORGANISM(S): Mus musculus 
2016-09-06 | E-GEOD-75648 | biostudies-arrayexpress
TranscriptomicsTn5 transposase-mediated library preparation of single-cell cDNAs for RNA-seq
Deep sequencing of single cell-derived genomic DNA and/or cDNAs brings novel insights into oncogenesis and embryogenesis. However, traditional library preparation for RNA-Seq requires multiple steps, including shearing the target DNA/RNA and following sequential enzymatic reactions, which result in ...
ORGANISM(S): Mus musculus 
2012-05-25 | E-GEOD-38198 | biostudies-arrayexpress
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