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TranscriptomicsExpression data from BMDCs treated with BI2536 or vehicle control and stimulated with LPS or poly(I:C)
We used microarrays to detail the global programme of gene expression underlying Polo-like kinase inhibition with BI 2536 compound in mouse bone marrow-derived dendritic cells (BMDCs) stimulated with Toll-like receptor agonists LPS and poly(I:C). CD11c+ BMDCs were treated for 1 hour with BI 2536 (1µ...
ORGANISM(S): Mus musculus 
2011-04-12 | E-GEOD-28520 | biostudies-arrayexpress
Transcriptomicsgene expression profiles in KRAS mutant A549 cells after BI-2536 and fasudil combination treatment
To identify the potential mechanisms of enhanced activity of combined inhibition of PLK1 and ROCK, we conducted a microarray analysis on gene expression profiles in KRAS mutant A549 cells. We used Affymetrix GeneChip PrimeView Human Gene Expression array to detail gene expression after indicated tr...
ORGANISM(S): Homo sapiens 
2014-08-29 | E-GEOD-60887 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Rattus norvegicus cardiomyocytes to investigate the effects of PD184352 and BI-D1870 on changes in expression induced by endothelin-1
Cardiomyocytes were exposed to PD184352, BI-D1870 or endothelin-1 alone, or to endothelin-1 in the presence of each inhibitor
ORGANISM(S): Rattus norvegicus 
2013-01-16 | E-MEXP-3679 | biostudies-arrayexpress
UnknownBi-Catalyzed Trifluoromethylation of C(sp2)-H Bonds under Light.
Not available
S-EPMC10690797 | biostudies-literature
UnknownRadical Activation of N-H and O-H Bonds at Bismuth(II).
Not available
S-EPMC9479083 | biostudies-literature
ProteomicsA highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer
Raw proteomic files Metin C, Saatci O, Rezaeian A-H, Rao CN, Beneker C, Taylor H, Pederson B, Chatzistamou I, Buckley B, Lessner S, Angel P, McInnes C, Sahin O. A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer. Ce...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-05-16 | MSV000094776 | MassIVE
GenomicsBifidobacterium pseudocatenulatum strain:Bi-OTA128 | isolate:a 66-year-old healthy woman
Bifidobacterium pseudocatenulatum strain:Bi-OTA128 | isolate:a 66-year-old healthy woman Genome sequencing
PRJNA808866 | ENA
ProteomicsIntegrated proteomic and transcriptomic analyses reveal the roles of Brucella BI-1 in cell division and membrane homeostasis of Brucella suis S2
To explore the role of Brucella BI-1 in Brucella suis S2, we constructed the Brucella BI-1 deletion mutant strain and its complementary strain. We then determined the effect of Brucella BI-1 deletion on the physiological characteristics of Brucella suis S2 and revealed them via integrated transcript...
ORGANISM(S): Brucella Suis Bv. 1 Str. S2 
2020-11-13 | PXD022537 |
Unknown{Bis[2-(diphenyl-phosphan-yl)phen-yl] ether-κP,P'}(1,1'-dibenz-yl-1H,1'H-4,4'bi-1,2,3-triazole-κN,N)copper(I) hexa-fluorido-phosphate dichloro-methane hemisolvate.
Not available
S-EPMC2915126 | biostudies-literature
TranscriptomicsANTICANCER AGENT P-bi-TAT LINKS THE THYROID HORMONE RECEPTOR ON INTEGRIN αvβ3 TO CANCER CELL METABOLISM/ATP GENERATION.
Microarray analysis was carried out on human GBM primary cells (GBM 10181360) and GBM cell line (U87) exposed to P-bi-TAT (10-6 M tetrac equivalent) for 24 h and 48 h. P-bi-TAT significantly downregulated electron transport chain genes ATP5A1 (ATP synthase A1), ATP51, ATP5G2, COX6B1 (cytochrome c ox...
ORGANISM(S): Homo sapiens 
2021-09-11 | GSE183776 | GEO
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