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MetabolomicsAltered metabolome and microbiome features provide clues in understanding irritable bowel syndrome and depression comorbidity

Irritable bowel syndrome (IBS) is one of the functional gastrointestinal disorders characterized by chronic and/or recurrent symptoms of abdominal pain and irregular defecation. Changed gut microbiota has been proposed to mediate IBS; however, contradictory results exist, and IBS-specific microbi...

2021-12-01 | MTBLS2774 | MetaboLights
ProteomicsITRAQ-based quantitative proteomics analysis of forest musk deer with pneumonia
Pneumonia can seriously threaten the life of forest musk deer (an endangered species). To gain a comprehensive understanding of pneumonia pathogenesis in forest musk deer, iTRAQ-based proteomics analysis was performed in diseased (Phe group) and normal (Ctrl group) lung tissues of forest musk deer t...
ORGANISM(S): Moschus Berezovskii 
PXD031240 |
ProteomicsToxicokinetics of arenobufagin and its cardiotoxicity mechanism exploration based on lipidomics and proteomics approaches in rats
In this study, the hearts used for proteomics analysis were obtained from rats randomly divided into three groups (6 rats in each group): a control group (a mixture of propanediol and sodium chloride solution), a low-dose ArBu group (ArBu suspension 60 mg/kg) and a high-dose ArBu group (ArBu suspens...
ORGANISM(S): Rattus Norvegicus 
PXD028622 |
ProteomicsTumour-associated high endothelial venules drive portal-specific immune evasion in lymph nodes via ALOX12
This project aims to characterize the endothelial cell proteome labeled by tumor-derived secreted Sema3C in metastatic lymph nodes using an in vivo TurboID-based proximity labeling strategy. EO771 breast cancer cells overexpressing either a secreted p65-Sema3C–TurboID fusion protein or TurboID alone...
ORGANISM(S): Mus Musculus 
2026-02-10 | PXD074282 |
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