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ProteomicsNuclear Condensation of NUP98-Fusion Proteins drives leukemogenic gene expression NUP98-fusion protein drive oncogenic gene expression via nuclear/biomolecular condensation
NUP98-fusion proteins cause leukemia via unknown molecular mechanisms. All NUP98-fusion proteins share an intrinsically disordered region (IDR) featuring >35 repeats of Phenylalanine-Glycine (FG) in the NUP98 N-terminus. Conversely, C-terminal NUP98-fusion partners often have critical functions in g...
ORGANISM(S): Homo sapiens (Human) 
2020-12-23 | PXD022518 | Pride
Aml Ap-ms Fusion protein Nup98 Bicon-ms Condensate 
TranscriptomicsNuclear Condensation of NUP98-Fusion Proteins drives leukemogenic gene expression
NUP98-fusion proteins cause acute myeloid leukemia via unknown molecular mechanisms. All NUP98-fusion proteins share an intrinsically disordered region (IDR) featuring >35 repeats of Phenylalanine-Glycine (FG) in the NUP98 N-terminus. Conversely, different C-terminal NUP98-fusion partners are often ...
ORGANISM(S): Mus musculus 
2021-02-16 | GSE159037 | GEO
UnknownBiomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression.
Not available
S-EPMC7116736 | biostudies-literature
GenomicsNuclear Condensation of NUP98-Fusion Proteins drives leukemogenic gene expression
Nuclear Condensation of NUP98-Fusion Proteins drives leukemogenic gene expression
PRJNA667460 | ENA
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