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TranscriptomicsThe histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival
We profiled basal and bicuculline+4-AP inducible mRNA expression in cultured mouse hippocampal neurons with or without viral shRNA mediated knockdown of Kdm6b We harvested mRNA from neurons under four conditions (pLKO vector/treatment control, pLKO vector/3hr bicuculline+4AP, Kdm6b knockdown/treatme...
ORGANISM(S): Mus musculus 
2014-06-12 | E-GEOD-58398 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse hippocampal slices after NMDA or forskolin-rolipram-0 Mg2+ or bicuculline treatment
Effect of different chemical stimuli (NMDA(N-methyl-D-aspartic acid), forskolin/rolipram/0 Mg, bicuculline) on gene expression after 1 h of stimulation in hippocampal slices
ORGANISM(S): Mus musculus 
2008-06-01 | E-MEXP-1184 | biostudies-arrayexpress
UnknownEffects of (+)-bicuculline, a GABAa receptor antagonist, on auditory steady state response in free-moving rats.
Not available
S-EPMC7380603 | biostudies-literature
TranscriptomicsIdentification of response genes upon neuronal activation in mouse cortical neurons
We search for developmental changes specific to humans by examining gene expression profiles in the human, chimpanzee and rhesus macaque prefrontal and cerebellar cortex. In both brain regions, developmental patterns were more evolved in humans than in chimpanzees. The major human specific genes in ...
ORGANISM(S): Mus musculus 
2012-02-02 | E-GEOD-29139 | biostudies-arrayexpress
UnknownGABAρ subunits confer a bicuculline-insensitive component to GFAP+ cells of cerebellum.
Not available
S-EPMC4267400 | biostudies-literature
UnknownBicuculline from <i>Forsythia suspensa</i> attenuates liver fibrosis via TLR4/MD2 inhibition and suppression of MyD88/NF-κB signaling.
Not available
S-EPMC12829150 | biostudies-literature
GenomicsMapping translation initiation sites by ribosome profiling in primary mouse cortical neurons treated with either DMSO or bicuculline
Mapping translation initiation sites by ribosome profiling in primary mouse cortical neurons treated with either DMSO or bicuculline
PRJNA1073923 | ENA
TranscriptomicsA comparative transcriptomics approach unveils networks of activity-driven neuronal gene expression
Primary cultured hippocampal neurons were infected with lentiviral particles bearing constitutively active versions of the transcription factors CREB, SRF, EGR1 and FOS to define the downstream genetic program associated with each of these paradigmatic transcription factors in neurons. For CREB, we ...
ORGANISM(S): Mus musculus 
2011-11-19 | E-MEXP-3167 | biostudies-arrayexpress
UnknownMapping responses to focal injections of bicuculline in the lateral parafacial region identifies core regions for maximal generation of active expiration.
Not available
S-EPMC11254382 | biostudies-literature
TranscriptomicsIsolation of a Novel Rat Neural Progenitor Clone that Expresses Dlx Family Transcription Factors and Gives Rise to Functional GABAergic Neurons in Culture
GABAergic interneurons are lost in conditions including epilepsy and CNS injury, but there are few culture models available to study their function. Towards the goal of obtaining renewable sources of GABAergic neurons, we used the molecular profile of a functionally-incomplete GABAergic precursor c...
ORGANISM(S): Rattus norvegicus 
2011-11-09 | E-GEOD-31635 | biostudies-arrayexpress
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