Sort   by:  
 Page size 
ProteomicsBioE3 enables the identification of bona fide targets of E3 ligases
The post-translational modification of proteins by ubiquitination is a highly regulated process that involves a dynamic, three-step enzymatic cascade, where more than 600 E3 ligases play a critical role in recognizing specific substrates for modification. Separating bona fide targets of E3s from E3-...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD041685 | Pride
E3-ligases Bioe3 Ubiquitination Proteomics 
UnknownBioE3 identifies specific substrates of ubiquitin E3 ligases.
Not available
S-EPMC10667490 | biostudies-literature
UnknownCullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome.
Not available
S-EPMC11841277 | biostudies-literature
ProteomicsChanges in Cereblon substrates landscape upon molecular glue treatment
The specificity of the ubiquitination process is mediated by the E3 ligases. Discriminating specific substrates of E3s from interacting proteins is one of the major challenges in the field. We previously developed BioE3, a biotin-based approach that uses BirA-E3 fusions together with ubiquitin fused...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055877 | Pride
Ubiquitination Cereblon Bioe3 
Sort   by:  
 Page size