Background: Cell line specific, genome-scale metabolic models enable rigorous and systematic in silico investigation of cellular metabolism. Such models have recently become available for Chinese hamster ovary (CHO) too. However, a key ingredient, namely an experimentally validat...
Cells use glycolytic intermediates for anabolism e.g., via the serine synthesis and pentose phosphate pathways. However, we still understand poorly how these metabolic pathways contribute to skeletal muscle cell biomass generation. The first aim of this study was therefore to identify enzymes tha...
Dried bulbs of Fritillaria thunbergii Miq. (Liliaceae family) are medicinal materials used to clear heat and resolve phlegm. However, premature plant etiolation during cultivation reduces yield and hampers the industrial development of these plants. This study compared agronomic traits, soil prop...