Sort   by:  
 Page size 
MetabolomicsIndustrial by-products as a novel circular source of biocompatible extracellular vesicles

Extracellular vesicles (EVs) constitute an intricate system of molecular exchange that has recently gained tremendous interest. However, sustainable sources of safe biological EVs remain scarce and elusive. In this study we explore and define the use of food industry byproducts (BP) as a circular...

2022-05-17 | MTBLS2801 | MetaboLights
MetabolomicsAn Expanded Database of High-Resolution MS/MS Spectra for Lichen Derived Natural Products

The history of lichen compound identification has long relied on techniques such as spot tests and TLC, which have been surpassed in sensitivity and accuracy by modern metabolomic techniques such as high-resolution MS/MS. In 2019, Olivier-Jimenez et al. released the Lichen DataBase (LDB), a libra...

2024-10-09 | MTBLS8109 | MetaboLights
MetabolomicsA Combined LC-MS Metabolomics- and 16S rRNA Sequencing Platform to Assess Interactions between Herbal Medicinal Products and Human Gut Bacteria in Vitro: a Pilot Study on Willow Bark Extract
Herbal preparations are complex mixtures of natural products, many of which are able to reach the distal gut. There, they influence the microbial communities, and can be metabolized into bioactive metabolites. The aim of this study was to establish an interdisciplinary platform to unravel interactio...
2017-12-14 | MTBLS479 | MetaboLights
UnknownAdvances in biopharmaceutical products for hemophilia.
Not available
S-EPMC11665423 | biostudies-literature
ProteomicsA Sensitive, Rapid, Robust and Reproducible Workflow for Host Cell Protein Profiling in Biopharmaceutical Process Development
There is a growing industry and regulatory need to detect host cell protein (HCP) impurities in the production of protein biopharmaceuticals, as certain HCPs can impact product stability, safety, and efficacy, even at low levels.1-6 In some cases, regulatory agencies require the identification as we...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-02 | PXD018427 | Pride
Monoclonal antibody (mab) Drug product (dp) Evosepone Drug substance (ds) Host cell proteins (hcps) Lc-ms/ms 
ProteomicsHost cell protein detection in antibody drug products
Detection and quantitation of host cell proteins in six antibody drug products using data dependent acquisition LC-MS/MS
ORGANISM(S): Cricetus cricetus 
2024-08-10 | PXD053529 | Pride
Drug product Recombinant therapeutic protein Biopharmaceutical manufacturing Chinese hamster ovary cells 
UnknownCurrent situation and future development of the biopharmaceutical industry in China: A mixed-method study.
Not available
S-EPMC9442039 | biostudies-literature
UnknownFeasibility analysis of automated cleaning in biopharmaceutical production using cleaning-in-place concepts from food production.
Not available
S-EPMC12497818 | biostudies-literature
UnknownMachine learning driven acceleration of biopharmaceutical formulation development using Excipient Prediction Software (ExPreSo).
Not available
S-EPMC12597001 | biostudies-literature
UnknownDevelopment and Validation of Quantitative Real-Time PCR for the Detection of Residual CHO Host Cell DNA and Optimization of Sample Pretreatment Method in Biopharmaceutical Products.
Not available
S-EPMC6717637 | biostudies-literature
Sort   by:  
 Page size