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ProteomicsSopD2-UltraID-HA_Styphimurium-HeLa_Brumell_2025
Dataset contains files from HeLa cells infected with UltraID-SopD2-HA-expressing Salmonella typhimurium. Cells were supplied with biotin and lysed in modified RIPA buffer. Lysates were incubated with streptavidin sepharose and captured proteins were digested with trypsin. Samples were analyzed on TI...
ORGANISM(S): Salmonella Typhimurium Dt104 (ncbitaxon:85569) Homo Sapiens (ncbitaxon:9606) 
2025-08-19 | MSV000098876 | MassIVE
ProteomicsVARS1 overexpression in hepatocellular carcinoma cell lines
VARS1 was transiently overexpressed in Hep3B and SNU-387 hepatocellular carcinoma-derived cell lines.
ORGANISM(S): Homo sapiens (Human) 
2024-12-02 | PXD056392 | Pride
Vars1 Hepatocellular carcinoma Liver 
ProteomicsHigher concentration of extracellular vesicles in plasma from ME/CFS patients, with protein cargo alterations implicating complement and coagulation pathways
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic and debilitating disease characterized by post-exertional malaise, fatigue and pain. Yet, its underlying biological mechanisms remain poorly understood. Extracellular vesicles (EVs) are nanoparticles carrying biological cargo a...
ORGANISM(S): Homo sapiens (Human) 
2026-08-24 | PXD072203 | Pride
Myalgic encephalomyelitis/chronic fatigue syndrome Extracellular vesicles Lc-ms/ms 
ProteomicsIdentification of fibroblast proteome in systemic sclerosis
Here the proteome of cultured human fibroblasts is determined by LC-MS/MS in the context of FHL1 or CD9 downregulation.
ORGANISM(S): Homo sapiens (Human) 
2026-09-22 | PXD062597 | Pride
Fhl1 Cell culture Cd9 Human Proteome Fibroblasts Systemic sclerosis 
ProteomicsPorin expression in clinical isolates of Klebsiella pneumoniae: a comparison of SDS-PAGE and MALDI-TOF/MS and limitations of whole genome sequencing analysis Porin expression in clinical isolates of Klebsiella pneumoniae: a comparison of SDS-PAGE and MALDI-TOF/MS and limitations of whole genome sequencing analysis
Precise definition of porin profiles is of critical importance to understand the role of porins in antimicrobial resistance. In this study, the outer membrane proteins (OMP) profiles of 26 clinical isolates of Klebsiella pneumoniae and of strain ATCC 13883 (wild-type) and ATCC 700603 (producing SHV-...
ORGANISM(S): Klebsiella pneumoniae subsp. rhinoscleromatis ATCC 13884 Bacteria 
2025-05-07 | PXD053879 | Pride
Porins Klebsiella Lcms/ms 
ProteomicsInterplay between cultured human osteoblastic and skeletal muscle cells: Effects of conditioned media on glucose and fatty acid metabolism
The interplay between skeletal muscle and bone is primarily mechanical, however, biochemical crosstalk by secreted mediators has recently gained increased attention. The aim of this study was to investigate metabolic effects of conditioned medium from osteoblasts (OB-CM) on myotubes and vice versa. ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD045723 | Pride
Energy metabolism  myokines  osteoblastic cells  osteokines  primary human myotubes 
ProteomicsCirculating human NK cells, metastatic colorectal cancer
Antibody-Dependent Cell-mediated Cytotoxicity (ADCC) induced by natural killer (NK) cells is one important mechanism by which cetuximab exerts its anti-tumoral effect. Therefore, molecular characterization of NK cells subpopulations may identify predictive biomarkers of cetuximab efficacy in mCRC pa...
ORGANISM(S): Homo sapiens (Human) 
2025-05-23 | PXD057989 | Pride
Nk cells Mcrc 
ProteomicsProteomic analysis of vascular tissue from critical limb ischemia mouse models treated with Etrinabdione
Vasculogenic therapies have been investigated for the treatment of peripheral artery disease (PAD) with very limited success in clinical trials. The isoform PP2A (protein phosphatase 2)/B55alpha inhibits the activity of the prolyl hydroxylase 2 (PHD2) and activates the hypoxia inducing factor-1alpha...
ORGANISM(S): Mus musculus (Mouse) 
2024-04-03 | PXD050360 | Pride
Vascular tissue Critical limb ischemia 
ProteomicsProteomic characterization of the effect of CBD in animal models of PWA
The effect of CBD was investigated in a preclinical model of PCOS generated by chronic exposure of female mice to DHT from weaning onwards. To exacerbate the metabolic complications in this model, PWA mice were fed a high-fat diet (HFD) for 18 weeks before initiation of the pharmacological treatment...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-05 | PXD061045 | Pride
Androgenization Liver Cannabidiol Obesity 
ProteomicsLabel free quantification approach comparing hepatic tissue from SCD and healthy mice
Sickle cell disease (SCD) is characterized by the expression of an abnormal hemoglobin variant (HbS) that promotes distortion and early destruction of red blood cells, resulting in hemolytic anemia, vaso-occlusive crisis, ischemia and, ultimately, tissue damage. Hepatic function is specially comprom...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-10 | PXD069285 | Pride
Liver Mice Sickle cell diasease 
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