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ProteomicsSWATH-MS proteomic analysis of primary human keratinocytes exposed to Cannabidiol
Primary human keratinocytes cultures were incubated with either DMSO or cannabidiol (10 uM) for 24 hours (N=4) to evaluate the effect of this compound over skin cells.
ORGANISM(S): Homo sapiens (Human) 
2019-10-16 | PXD013956 | Pride
Keratinocytes Cannabidiol Swath 
TranscriptomicsEffects of (-)-cannabidiol on human sebocytes
In the current study, we aimed at exploring the effects of the major non-psychotropic phytocannabinoid of Cannabis sativa, (-)-cannabidiol (CBD), on human sebaceous gland functions. We found that CBD behaved as a highly effective anti-acne agent, targeting all the three key, sebocyte-specific steps ...
ORGANISM(S): Homo sapiens 
2014-07-29 | E-GEOD-57571 | biostudies-arrayexpress
ProteomicsShotgun proteomic elucidation of Synergistic mechanisms of Cannabidiol and SN-38 in the MCF7 cells
We evaluted the synergyistic interactions of cannabidiol (CBD) with standard chemotherapeutic agents such as Docetaxel (DOC), doxorubicin (DOX), paclitaxel (PTX), vinorelbine (VIN), and 7-Ethyl-10-hydroxycamptothecin (SN38) in MCf7 cells ultising different synergy metrics. Then we explored the syner...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD026587 | Pride
Breast cancer Proteomics Mcf7 Synergy Cannabidiol Sn-38 Cbd 7-ethyl-10-hydroxycamptothecin 
GenomicsRNA-Seq analysis of primary human keratinocytes exposed to Cannabidiol
RNA-Seq analysis of primary human keratinocytes exposed to Cannabidiol
PRJNA544069 | ENA
ProteomicsIdentification of Cannabidiol interactome in K562 cells
Cannabidiol (CBD) showed antiproliferative activity and induction of apoptosis in chronic myelogenous leukaemia cancer cells (K562 cells). A consolidated DARTS (Drug Affinity Response Target Stability) and t-LIP-MRM (targeted- Limited Proteolysis-Multiple Reaction Monitoring Mass spectrometry) platf...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD036650 | Pride
Cbd  k562 cells  top2a  darts  t-lip-mrm  chemoproteomics  mass spectrometry 
GenomicsEffects of cannabidiol on the inflammation-stimulated keratinocytes
Effects of cannabidiol on the inflammation-stimulated keratinocytes
PRJNA638292 | ENA
GenomicsCannabidiol exerts antiinflammatory effects but maintains T effector memory cell differentiation in humans
Cannabidiol exerts antiinflammatory effects but maintains T effector memory cell differentiation in humans
PRJNA1293451 | ENA
ProteomicsCannabidiol displays proteomic similarities to antipsychotics in cuprizone-exposed human oligodendrocytic cell line MO3.13
We employed nano-chromatography coupled with mass spectrometry to investigate the proteomic response to benztropine,cannabidiol, clozapine, and haloperidol, both in healthy oligodendrocytic cells and in a cuprizone-based toxicity model, using the human oligodendrocyte precursor cell line MO3.13.
ORGANISM(S): Homo sapiens (Human) 
2021-11-11 | PXD028419 | Pride
Phytocannabinoid Schizophrenia Haloperidol Mo3.13 cell line Benztropine Proteome Clozapine 
TranscriptomicsCannabidiol exerts antiinflammatory effects but maintains T effector memory cell differentiation in humans
Cannabidiol is widely available and often used for pain management. Individuals with kidney disease or renal allografts have limited analgesia options. We conducted a Phase 1 healthy volunteer study to compare the peripheral immune cell distribution before (pre-cannabidiol) and after exposure to can...
ORGANISM(S): Homo sapiens 
2025-11-07 | GSE303537 | GEO
TranscriptomicsCannabidiol exerts antiinflammatory effects but maintains T effector memory cell differentiation in humans
Cannabidiol is widely available and often used for pain management. Individuals with kidney disease or renal allografts have limited analgesia options. We conducted a Phase 1 healthy volunteer study to compare the peripheral immune cell distribution before (pre-cannabidiol) and after exposure to can...
ORGANISM(S): Homo sapiens 
2025-11-07 | GSE303068 | GEO
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