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MetabolomicsMetabolic Biomarkers of Treatment-Resistant Schizophrenia and Cognitive Correlates: Insights from a Machine Learning

Metabolic Biomarkers of Treatment-Resistant Schizophrenia and Cognitive Correlates: Insights from a Machine Learning

2027-02-05 | MTBLS14005 | MetaboLights
MetabolomicsUntargetted lipidomics dataset: LC-MS analysis in two postmortem brain areas of healthy individuals and schizophrenia patients.

Schizophrenia is a common mental illness. It is a complex disorder with many symptoms and cognitive impairments. Despite extensive study, the molecular mechanisms of this disease are still unknown. Present time studies on the lipid composition of the human brain are extremely fragmented. Of the p...

2024-06-04 | MTBLS8955 | MetaboLights
MetabolomicsUntargeted 1 H NMR-based metabolomics unveils distinct circulating biochemical signatures between treatment-resistant and non-treatment-resistant Schizophrenia patients: a pilot study

Schizophrenia is a severe psychiatric disorder impacting roughly 1% of individuals. The effectiveness of antipsychotic therapy greatly varies, with around 30% of patients categorised as treatment-resistant (TRS). TRS is characterised by a lack of response to at least two clinical trials invo...

2025-10-01 | MTBLS12709 | MetaboLights
TranscriptomicsDisrupted circadian rhythms in a mouse model of schizophrenia
Disrupted circadian rhythms in a mouse model of schizophrenia
ORGANISM(S): Mus musculus 
2012-03-01 | E-MEXP-3493 | biostudies-arrayexpress
ProteomicsSchizophrenia Proteome Data High Resolution Method
PTM-tolerant quantitative proteome analysis of plasma collected from schizophrenia patients and nonspychiatric healthy controls.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-03-02 | MSV000086977 | MassIVE
ProteomicsSchizophrenia Plasma Metabolome Analysis
Metabolomics analysis of plasma collected from patients with schizophrenia and non-psychiatric control subjects.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-03-02 | MSV000086975 | MassIVE
TranscriptomicsGenotyping data from 54 patients with deficit schizophrenia
Schizophrenia is a severe psychiatric disease with complex etiology, affecting approximately one percent of the general population. Most genetic studies so far focused on disease association with common genetic variation such as single nucleotide polymorphisms, but recently it has become apparent th...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-12714 | biostudies-arrayexpress
MetabolomicsMetabolomic study on a schizophrenia and type 2 diabetes susceptibility gene
Not available
ORGANISM(S): Homo sapiens 
ST000568 | MetabolomicsWorkbench
TranscriptomicsDNA methylation in schizophrenia in different patient-derived cell types
DNA methylation of gene promoter regions represses transcription and is a mechanism via which environmental risk factors could affect cells during development in individuals at risk for schizophrenia. We investigated DNA methylation in patient-derived cells that might shed light on early development...
ORGANISM(S): Homo sapiens 
2017-11-01 | E-MTAB-5016 | biostudies-arrayexpress
ProteomicsSchizophrenia brain proteomic analysis
The purpose of the study was to identify altered molecular networks in the prefrontal cortex of schizophrenia patients by comparing protein expression levels in autopsied brains of patients (n=10) and controls (n=10), using aquantitative proteomics.
ORGANISM(S): Homo Sapiens (human) 
2018-01-01 | PXD008227 | JPOST Repository
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