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MetabolomicsStreamlined identification of strain engineering targets for bioprocess improvement using metabolic pathway enrichment analysis
Metabolomics is a powerful tool for the identification of genetic targets for bioprocess optimisation. However, in most cases, only the biosynthetic pathway directed to product formation is analysed, limiting the identification of these targets. Some studies have used untargeted metabolomics, allowi...
2023-08-31 | MTBLS6667 | MetaboLights
ProteomicsProteomic study of S erythrea bioprocess
Proteome composition of Saccharopolyspora erythrea during the fermentation bioprocess was studied. Samples were collected at two timepoints (prior to the rapid growth phase and at the start of the rapid growth phase), and relative differences in protein abundance were determined by spectral counting...
ORGANISM(S): Saccharopolyspora erythraea (Streptomyces erythraeus) 
2016-05-26 | PXD002472 | Pride
Saccharopolyspora erythrea Bioprocess Lc-ms/ms 
UnknownDesign of experiment (DOE) applied to artificial neural network architecture enables rapid bioprocess improvement.
Not available
S-EPMC8144078 | biostudies-literature
MetabolomicsOn-line targeted metabolomics for real-time monitoring of relevant compounds in fermentation processes
Fermentation monitoring is a powerful tool for bioprocess development and optimisation. On-line metabolomics is a technology that is starting to gain attention as a bioprocess monitoring tool, allowing the direct measurement of many compounds in the fermentation broth at a very high time resolution....
2024-03-05 | MTBLS7889 | MetaboLights
UnknownTeaching bioprocess engineering to undergraduates: Multidisciplinary hands-on training in a one-week practical course.
Not available
S-EPMC6680437 | biostudies-literature
UnknownBioprocess development for microbial production and purification of cellobiose lipids by the smut fungus Ustilago maydis DSM 4500.
Not available
S-EPMC11865158 | biostudies-literature
UnknownBioprocess exploitation of microaerobic auto-induction using the example of rhamnolipid biosynthesis in Pseudomonas putida KT2440.
Not available
S-EPMC11742490 | biostudies-literature
MetabolomicsOn-line untargeted metabolomics monitoring of an Escherichia coli succinate fermentation process
The real-time monitoring of metabolites (RTMet) is instrumental for the industrial production of biobased fermentation products. This study shows the first application of untargeted on-line metabolomics for the monitoring of undiluted fermentation broth samples taken automatically from a 5 L bioreac...
2023-04-26 | MTBLS5197 | MetaboLights
TranscriptomicsGene expression profiling of Chinese Hamster Ovary production cell lines
The dataset set consists of 295 microarrays from 121 individual CHO cultures producing a range of biologics including monoclonal antibodies, fusion proteins and therapeutic factors; non-producing cell lines were also included. Samples were taken from a wide range of process scales and formats that v...
ORGANISM(S): Cricetulus griseus 
2011-07-27 | E-GEOD-30321 | biostudies-arrayexpress
UnknownImpact of Autoclaving on the Material Properties of Vat-Photopolymerization-Produced Components Intended for Bioprocess Engineering.
Not available
S-EPMC12566325 | biostudies-literature
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