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TranscriptomicsCfp1 is required for gene expression dependent H3K4me3 and H3K9 acetylation in embryonic stem cells (RNA-Seq)
Trimethylation of histone H3 lysine 4 (H3K4me3) accumulates at promoters in a gene activity dependant manner. The Set1 complex is responsible for most H3K4me3 in somatic cells and contains the conserved subunit Cfp1, which is implicated in targeting the Set1 complex to CpG islands in mammals. In mou...
ORGANISM(S): Mus musculus 
2014-08-20 | E-GEOD-53489 | biostudies-arrayexpress
GenomicsCfp1 is required for gene expression dependent H3K4me3 and H3K9 acetylation in embryonic stem cells (ChIP-Seq)
Trimethylation of histone H3 lysine 4 (H3K4me3) accumulates at promoters in a gene activity dependant manner. The Set1 complex is responsible for most H3K4me3 in somatic cells and contains the conserved subunit Cfp1, which is implicated in targeting the Set1 complex to CpG islands in mammals. In mou...
ORGANISM(S): Mus musculus 
2014-08-20 | E-GEOD-53490 | biostudies-arrayexpress
GenomicsCell Type-Specific DNA Methylation at Intragenic CpG Islands in the Immune System
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2011-05-23 | E-GEOD-25689 | biostudies-arrayexpress
TranscriptomicsChIP-Seq of ES-E14 mouse embryonic stem cells investigating changes in Sall4
Sall4 is a stem cell factor which is important for embryogenesis. We have genetically modified Sall4 in mouse embryonic stem cells to access the preference of Sall4 binding site. There are three different genetic modifications for the ES cells in the form of Sall4 Knockout (KO), Sall4 Zinc Finger Cl...
ORGANISM(S): Mus musculus 
2021-01-05 | E-MTAB-9197 | biostudies-arrayexpress
GenomicsCell Type-Specific DNA Methylation at Intragenic CpG Islands in the Immune System (MAP-Seq and ChIP-Seq data)
Human and mouse genomes contain a similar number of CpG islands (CGIs), which are discrete CpG-rich DNA sequences associated with transcription start sites. In both species, about 50% of all CGIs are remote from annotated promoters, but nevertheless often have promoter-like features. To document the...
ORGANISM(S): Mus musculus 
2011-05-23 | E-GEOD-25688 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of mouse embryonic stem cells in response to changes in Sall4
Sall4 is a stem cell factor which is important for embryogenesis. We have genetically modified Sall4 in mouse embryonic stem cells to access the transcriptional changes. There are three different genetic modifications for the ES cells in the form of Sall4 Knockout (KO), Sall4 Zinc Finger Cluster 4 M...
ORGANISM(S): Mus musculus 
2021-01-05 | E-MTAB-7343 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Sall4 is a stem cell factor which is important for embryogenesis. We have genetically modified Sall4 in mouse embryonic stem cells to access the transcriptional changes. There are three different genetic modifications for the ES cells in the form of Sall4 Knockout (KO), Sall4 Zinc Finger Cluster 4 M...
ORGANISM(S): Mus musculus 
2021-01-05 | E-MTAB-7655 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of human brain, spleen, skeletal muscle and whole blood identifies tissue-specific methylation at developmental gene loci
To compare the CpG Island methylome of human tissues.
ORGANISM(S): Homo sapiens 
2008-01-09 | E-MEXP-1391 | biostudies-arrayexpress
TranscriptomicsTimecourse RNA-seq of mouse embryonic stem cells during neural differentiation
Sall4 is a stem cell factor which is important for embryogenesis. We have genetically modified Sall4 in mouse embryonic stem cells to access the transcriptional changes. There are three different genetic modifications for the ES cells in the form of Sall4 Knockout (KO), Sall4 Zinc Finger Cluster 4 M...
ORGANISM(S): Mus musculus 
2021-01-05 | E-MTAB-9198 | biostudies-arrayexpress
TranscriptomicsATAC-seq of mouse embryonic stem cells
To identify the accessible chromatin in wild-type mouse embryonic stem cells (mESCs), we performed ATAC-seq in mESCs.
ORGANISM(S): Mus musculus 
2021-01-05 | E-MTAB-9245 | biostudies-arrayexpress
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