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UnknownCharacteristics of peak exposure to black carbon pollution in school, commute and home environments among school children in an urban community.
Not available
S-EPMC9900622 | biostudies-literature
TranscriptomicsGene expression and genotype in normal heart
Genome-wide association studies have identified a small region at chromosome 9p21.3 strongly associated with coronary heart disease risk. The region contains no protein-coding genes and the mechanism underlying its association with heart disease is unknown. We investigated associations between rs133...
ORGANISM(S): Homo sapiens 
2012-07-03 | E-GEOD-22253 | biostudies-arrayexpress
TranscriptomicsExpression data from a 24h time series of dexamethasone treatment for mouse bone marrow derived macrophages
Macrophages are amongst the major targets of glucocorticoids (GC) as therapeutic anti-inflammatory agents. Here we show that GC treatment of mouse and human macrophages initiates a cascade of induced gene expression including many anti-inflammatory genes. Inducible binding of the glucocorticoid rec...
ORGANISM(S): Mus musculus 
2015-12-17 | E-GEOD-61879 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type, p53 Ser389 phosphorylation site point mutant and p53 knock-out mouse embryonic fibroblasts after exposure to UV radiation for different lengths of time
Comparison of responses of mouse wild-type, p53 Ser389 phosphorylation site point mutant and full knock-out mutant MEF cells to UV-C-radiation in time
ORGANISM(S): Mus musculus 
2008-06-01 | E-MEXP-1397 | biostudies-arrayexpress
TranscriptomicsSingle cell Hi-C reveals cell-to-cell variability in chromosome structure
Large-scale chromosome structure and spatial nuclear arrangement have been linked to control of gene expression and DNA replication and repair. Genomic techniques based on chromosome conformation capture assess contacts for millions of loci simultaneously, but do so by averaging chromosome conformat...
ORGANISM(S): Mus musculus 
2013-09-26 | E-GEOD-48262 | biostudies-arrayexpress
GenomicsNeuroblastoma Genome-Wide Association Study (NBL-GWAS)

Neuroblastoma is a malignancy of the developing sympathetic nervous system that most commonly affects young children and is often lethal. The etiology of this embryonal cancer is not known.

We have performed a whole genome scan for association of neuroblastoma with SNP genotypes an...

phs000124.v2.p1 | EGA
TranscriptomicsmRNA Sequencing Reveals Altered Synaptic Vesicular Transport in Post-Mortem Cerebellum
Schizophrenia (SCZ) is a common, disabling mental illness with high heritability but complex, poorly understood genetic etiology. As the first phase of a genomic convergence analysis of SCZ, we generated 16.7 billion nucleotides of short read, shotgun sequences of cDNA from post-mortem cerebellar c...
ORGANISM(S): Homo sapiens 
2009-08-29 | E-GEOD-12297 | biostudies-arrayexpress
UnknownGWAS meta-analysis of 16 852 women identifies new susceptibility locus for endometrial cancer.
Not available
S-EPMC5868213 | biostudies-literature
TranscriptomicsUV-C dose and time range finding study on Mouse Embryonic Fibroblasts (MEFs)
In molecular biology, the design of mechanistic experiments has to be optimized by considering statistical and biological principles. In contrast to statistical principles, biological principles of experimental design are not universally formulated. In an attempt to pinpoint generally acceptable rul...
ORGANISM(S): Mus musculus 
2014-09-01 | E-GEOD-50930 | biostudies-arrayexpress
TranscriptomicsThe ets transcription factor ELF5 suppresses the estrogen sensitive phenotype and contributes to antiestrogen resistance in luminal breast cancer. [human]
The ets transcription factor ELF5 specifies the differentiation of mammary progenitor cells to establish the milk-secreting lineage. ER- and poor prognosis basal breast cancers arise from this progenitor cell and these cancers express high levels of Elf5. Knockdown of ELF5 expression in basal breast...
ORGANISM(S): Homo sapiens 
2012-12-27 | E-GEOD-30405 | biostudies-arrayexpress
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