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TranscriptomicsChromatin immunopreciptation genome wide location of H2A.Z binding sites in yeast yeast
genome wide location of H2A.Z binding sites in yeast Saccharomyces cerevisiae. Nucleosome density controled with H2B ChIP. Hybridization control ChIP H2AZ/H2AZ and H2A/H2B.
ORGANISM(S): Saccharomyces cerevisiae 
2005-12-31 | E-MEXP-396 | biostudies-arrayexpress
TranscriptomicsArabidopsis lyrata strain:MN47 Transcriptome or Gene expression
Illumina, strand-specific RNA sequencing of A lyrata for gene annotation.
ORGANISM(S): Arabidopsis lyrata 
2013-06-26 | E-MTAB-5072 | biostudies-arrayexpress
GenomicsClassifying leukemia types with chromatin conformation data (ChIP-Seq)
Background: Although genetic or epigenetic alterations have shown to affect the three-dimensional organization of genomes, the utility of chromatin conformation in the classification of human disease has never been addressed. Results: Here, we explore whether chromatin conformation can be used to cl...
ORGANISM(S): Homo sapiens 
2014-02-27 | E-GEOD-55407 | biostudies-arrayexpress
GenomicsThe relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts [Whole genome bisulfite sequencing]
Background DNA methylation has long been known to play an essential role in the epigenetic regulation of gene expression and other cellular functions, and has been in some cases linked to genetic variation. While its presence near the transcription start site of a gene has been associated with reduc...
ORGANISM(S): Homo sapiens 
2014-01-25 | E-GEOD-54373 | biostudies-arrayexpress
TranscriptomicsClassifying leukemia types with chromatin conformation data (5C)
Background: Although genetic or epigenetic alterations have shown to affect the three-dimensional organization of genomes, the utility of chromatin conformation in the classification of human disease has never been addressed. Results: Here, we explore whether chromatin conformation can be used to cl...
ORGANISM(S): Homo sapiens 
2014-02-27 | E-GEOD-55406 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of human cell lines with oestrogen receptor (ER), the E2F transcription factor 4 (E2F4),
The Goal of the experiment was to validate the predicted regulatory modules identified by an algorithm.For this we took advantage of the the genome-wide location analysis technique (or ?ChIP/chip?). We selected modules predicted to be bound by the estrogen receptor (ER), the E2F transcription factor...
ORGANISM(S): Homo sapiens 
2006-05-01 | E-MEXP-471 | biostudies-arrayexpress
TranscriptomicsThe relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts [methylation profiling]
Background DNA methylation has long been known to play an essential role in the epigenetic regulation of gene expression and other cellular functions, and has been in some cases linked to genetic variation. While its presence near the transcription start site of a gene has been associated with red...
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-52025 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse hearts from mutants lacking estrogen-related receptor alpha (ERRalpha), a nuclear receptor
Total RNA was isolated from 3 WT and 3 ERRalpha null hearts and independent hybridizations were performed using MOE430 2.0 microarrays. Expression profiling was conducted to determine changes in gene expression in hearts lacking ERRa. The expression of genes involved in heart and muscle development,...
ORGANISM(S): Mus musculus 
2007-11-10 | E-GEOD-7196 | biostudies-arrayexpress
GenomicsPopulation whole-genome bisulfite sequencing across two tissues highlights environment as principal source of human methylome variation
The study includes whole-genome bisulfite sequencing (WGBS) on 34 adipose (7 MZ pairs, 6 DZ pairs and 8 singletons) and 27 blood (7 MZ pairs, 6 DZ pairs and 1 singleton) DNA samples derived from a total of 43 female twins belonging to the MuTHER/TwinsUK cohort. We generated 11.5 billion 100bp paired...
EGAS00001001569 | EGA
TranscriptomicsThe relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts [expression profiling]
Background: DNA methylation has long been known to play an essential role in the epigenetic regulation of gene expression and other cellular functions, and has been in some cases linked to genetic variation. While its presence near the transcription start site of a gene has been associated with red...
ORGANISM(S): Homo sapiens 
2013-12-13 | E-GEOD-53243 | biostudies-arrayexpress
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