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ProteomicsBalanced Input from the tRNA Prenyltransferase MiaA Controls the Stress Resistance and Virulence Potential of Extraintestinal Pathogenic Escherichia coli
In Escherichia coli, the highly conserved enzymes MiaA and MiaB mediate the sequential prenylation and methylthiolation of adenosine-37 within tRNAs that decode UNN codons. We found that MiaA, but not MiaB, is critical to the fitness and virulence of extraintestinal pathogenic E. coli (ExPEC), a maj...
ORGANISM(S): Escherichia coli 
2022-02-14 | PXD024782 | Pride
Expec Trna modification Extraintestinal pathogenic escherichia coli Frameshifting Urinary tract infection Bacterial fitness Translation Translational regulation Sepsis Stress response Uropathogenic Miab Miaa Fidelity Proteome 
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