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TranscriptomicsRNA-seq transcriptomes of term not in labour and term in labour human myometrial tissue
Purpose: To chart the human myometrial transcriptomes before and after the onset of labour. Methods: Tophat splice junction mapping of paired-end reads, HTSeq to generate counts, cufflinks to track transcripts, DESeq, edgeR and baySeq to detect differentially expressed genes and principal component ...
ORGANISM(S): Homo sapiens 
2014-02-17 | E-GEOD-50599 | biostudies-arrayexpress
ProteomicsNRF2 activation reprogrammes defects in oxidative metabolism to restore macrophage function in COPD
Rationale: COPD (Chronic Obstructive Pulmonary Disease) is a disease characterized by persistent airway inflammation and disordered macrophage function. The extent to which alterations in macrophage bioenergetics contribute to impaired antioxidant responses and disease pathogenesis has yet to be ful...
ORGANISM(S): Homo sapiens (Human) 
2023-04-02 | PXD040504 | Pride
Metabolism Macrophage Malic enzyme 1. Chronic obstructive pulmonary disease Nuclear factor erythroid 2–related factor 2 (nrf2) 
ProteomicsSpecies identification of early colonial bone artefacts excavated from Pyrmont, Australia, by mass spectrometric identification of collagen peptides
Zooarchaeology by Mass Spectrometry (ZooMS) is a rapidly developing and increasingly utilised peptide mass fingerprinting (PMF) technique that analyses Collagen 1A1 and 1A2 marker peptides for the genus- or species-level identification of fragmentary bones in the archaeological record. Traditionally...
ORGANISM(S): Bos taurus (Bovine) 
2023-11-29 | PXD032926 | Pride
Lc-msms Collagen 
MetabolomicsAmphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism, lipid transport and oxidative stress response

Amphotericin B is increasingly used in treatment of leishmaniasis. Here, fourteen independent lines of Leishmania mexicana and one L. infantum line were selected for resistance to either amphotericin B or the related polyene antimicrobial, nystatin. Sterol profiling revealed tha...

2022-09-22 | MTBLS2744 | MetaboLights
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