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MetabolomicsExpanding the clinical use of DBS: through a metabolomic and a lipidomic evaluation

Personalized medicine aims to tailor healthcare to individual characteristics, relying on precise biological data and patient monitoring. Metabolomics and lipidomics play a key role in this approach, providing real-time insights into metabolic states and enabling accurate diagnosis and treatment ...

2026-02-25 | MTBLS13382 | MetaboLights
UnknownShort-Term Heart Rate Variability in Metabolic Syndrome: A Systematic Review and Meta-Analysis.
Not available
S-EPMC10532399 | biostudies-literature
GenomicsGenome-wide maps of RAP1 binding sites.
By performing chromatin immunoprecipitation coupled with ultra-high-throughput sequencing (ChIP-seq), we find that RAP1 binds to telomeres as well as to extra-telomeric sites through the (TTAGGG)2 consensus motif. Extra-telomeric RAP1 binding sites are particularly abundant at subtelomeric regions, ...
ORGANISM(S): Mus musculus 
2010-07-10 | E-GEOD-20867 | biostudies-arrayexpress
TranscriptomicsRoles of mammalian Rap1 in TERT recruitment to chromatin, subtelomeric gene silencing and transcriptional regulation
Repressor-activator protein 1 (scRap1) is the major binding activity at Saccharomyces cerevisiae telomeres, with roles in telomere length regulation and establishment of subtelomeric silencing by recruiting the Sir proteins. scRap1 also acts as a transcription factor controlling the expression of ri...
ORGANISM(S): Mus musculus 
2010-07-10 | E-GEOD-19011 | biostudies-arrayexpress
UnknownSmall extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice.
Not available
S-EPMC9581480 | biostudies-literature
TranscriptomicsSox4 links tumor suppression to accelerated aging in mice [Hair regeneration]
Sox4 is a transcription factor expressed during embryonic development and some adult tissues such as lymphoid organs, pancreas, intestine and skin. During embryogenesis, Sox4 regulates the survival of mesenchymal and neural progenitors, lymphocyte and myeloid differentiation, and pancreatic, bone an...
ORGANISM(S): Mus musculus 
2015-05-20 | E-GEOD-58153 | biostudies-arrayexpress
TranscriptomicsSox4 links tumor suppression to accelerated aging in mice [Telogen]
Sox4 is a transcription factor expressed during embryonic development and some adult tissues such as lymphoid organs, pancreas, intestine and skin. During embryogenesis, Sox4 regulates the survival of mesenchymal and neural progenitors, lymphocyte and myeloid differentiation, and pancreatic, bone an...
ORGANISM(S): Mus musculus 
2015-05-20 | E-GEOD-58154 | biostudies-arrayexpress
Unknownp53 prevents entry into mitosis with uncapped telomeres.
Not available
S-EPMC4959573 | biostudies-literature
TranscriptomicsPrimary murine embryonic fibroblasts (MEFs): Cdk7 wild type versus Cdk7 KO
Transcriptional profiling of primary Cdk7lox/lox MEFs comparing Adeno-Cre vs Adeno-GFP infected controls. Samples were obtained 7 days after the Adeno-Cre mediated elimination of Cdk7. Goal was to determine the effects of Cdk7 elimination on RNA polII-mediated transcription. Two-condition experiment...
ORGANISM(S): Mus musculus 
2012-04-17 | E-GEOD-36050 | biostudies-arrayexpress
UnknownIs novel research worth doing? Evidence from peer review at 49 journals.
Not available
S-EPMC9704701 | biostudies-literature
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