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Research Question: Can metabolomic profiling of blastocyst spent culture medium (SCM) serve as a non-invasive tool to predict live birth?

Design: This pilot study investigated the association between metabolite profiles in SCM and clinical outcomes following single blastocyst transfer. Seve...

2026-02-13 | MTBLS13898 | MetaboLights
Pluripotent stem cell lines can be derived from blastocyst embryos, which yield embryonic stem cell lines (ES cells), as well as the post-implantation epiblast, which gives rise to epiblast stem cell lines (EpiSCs). Remarkably, ES cells and EpiSCs display profound differences in the combination of g...
ORGANISM(S): Mus musculus 
Functional profile of bovine blastocyst-derived trophoblast cells
ORGANISM(S): Bos Taurus (ncbitaxon:9913) 
2018-11-13 | MSV000083135 | MassIVE
Microarray analysis was performed in ooplast samples to identify gene expression profiles associated with the embryo capacity to develop to blastocyst stage A fraction of the cytoplasm from in vitro matured oocytes was collected and snap frozen. The oocytes were chemically activated and presumptive ...
ORGANISM(S): Bos taurus 
Establishment of pregnancy in ruminants requires blastocyst growth to form an elongated conceptus that produces interferon tau, the pregnancy recognition signal, and initiates implantation. Blastocyst growth and development requires secretions from the uterine endometrium. An early increase in circu...
ORGANISM(S): Ovis aries 
Comparative trascriptomic analysis between porcine early-blastocyst and Hatched blastocyst collected around day 5-6 direct comparison with dye-swap; two different arrays with 6 Samples each
ORGANISM(S): Sus scrofa 
The maternal tract plays a critical role in the success of early embryonic development providing an optimal environment for establishment and maintenance of pregnancy. Preparation of this environment requires an intimate dialogue between the embryo and her mother. To advance our understanding of the...
ORGANISM(S): Sus scrofa 
Day5-6 porcine blastocyst gene expression profiling dye-swaped loop design with 3 biological replicates of Day5-6 blastocyst
ORGANISM(S): Sus scrofa 
Many mammals can temporally uncouple conception from parturition by pacing down their development around the blastocyst stage. In mice, this dormant state is achieved by decreasing the activity of the growth-regulating mTOR signaling pathway1. It is unknown whether this ability is conserved in mamma...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2024-08-06 | PXD029513 | Pride
Human blastoids model blastocyst development and implantation
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