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TranscriptomicsPhylogenetic, microbiological and glycoside hydrolase diversities within the extremely thermophilic, plant biomass-degrading genus Caldicellulosiruptor
Phylogenetic, microbiological and comparative genomic analysis was used to examine the diversity among members of the genus Caldicellulosiruptor with an eye towards the capacity of these extremely thermophilic bacteria for degrading the complex carbohydrate content of plant biomass. Seven species fr...
ORGANISM(S): Caldicellulosiruptor lactoaceticus 
2010-11-29 | E-GEOD-23606 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type and A-C/EBP transgenic mouse embryonic fibroblasts during adipogenesis to identify C/ebp alpha target genes
This experiment was designed to identify C/ebp alpha target genes during the process of adipogenesis by means of comparison of differentiating (wild-type) cells to a perturbation model (transgenic cells). For this, gene expression profiling during adipogenesis of mouse embryonic fibroblasts (MEFs) ...
ORGANISM(S): Mus musculus 
2009-07-02 | E-MARS-11 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of non-small cell lung carcinoma cell line H1975 treated with cisplatin or BMS-69014 a novel panHER/VEGFR inhibitor
Non-small cell lung cancer (NSCLC) with activating mutations in the epidermal growth factor receptor (EGFR) responds to EGFR tyrosine kinase inhibitors such as erlotinib. However, secondary somatic EGFR mutations (e.g. T790M) confer resistance to erlotinib. BMS-690514, a novel panHER/VEGFR inhibitor...
ORGANISM(S): Homo sapiens 
2007-07-24 | E-TABM-239 | biostudies-arrayexpress
UnknownA Cycle of Ubiquitination Regulates Adaptor Function of the Nedd4-Family Ubiquitin Ligase Rsp5.
Not available
S-EPMC7197006 | biostudies-literature
TranscriptomicsTranscription profiling by array of human sperm from normospermic and teratozoospermic individuals
Normal human spermatogenesis concludes with the formation of large numbers of morphologically well developed spermatozoa. While transcriptionally quiescent these cells carry an RNA payload that reflects the final spermiogenic phase of transcription. We report here the spermatozoal transcript profile...
ORGANISM(S): Homo sapiens 
2007-11-11 | E-GEOD-6872 | biostudies-arrayexpress
ProteomicsAge-dependent increase in Schmidt-Lanterman incisures and a Cadm4 associated membrane skeletal complex in fatty acid 2-hydroxylase deficient mice, a mouse model of spastic paraplegia SPG35
Fatty acid 2-hydroxylase (FA2H) is responsible for the synthesis of 2-hydroxylated fatty acids, which are a building block of sphingolipids. This 2-hydroxylated sphingolipids can be found in various tissues such as brain, spinal cord, skin, testis, ovary, kidney, stomach, or intestine with a notably...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-22 | PXD030244 | Pride
Isobaric labelling Schmidt-lanterman incisures Mice Hereditary spastic paraplegia type 35 Sphingolipids Neurodegeneration Sciatic nerves Disease model Fa2h Tmt Time course Myelin Fatty acid hydroxylation Pns Fatty acid 2-hydroxylase 
TranscriptomicsTranscription profiling of fission yeast as telomeres shorten in trt1- strains, and to compare survivors with linear and circular chromosomes
Time course experiment to watch RNA expression profiles as telomeres shorten in trt1- strains, and to compare survivors with linear and circular chromosomes.
ORGANISM(S): Schizosaccharomyces pombe 
2005-03-01 | E-MEXP-201 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast timecourse mcs6 mutant
The fission yeast Mcs6-Mcs2-Pmh1 complex (homologous to metazoan Cdk7-cyclin HMat1) performs dual functions: in cell cycle control, as a CDK-activating kinase; and in transcription by RNA polymerase (Pol) II, as part of TFIIH. It is unknown whether that linkage serves to coordinate gene expression w...
ORGANISM(S): Schizosaccharomyces pombe 
2004-11-01 | E-MEXP-192 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast mutants sep10 and sep15
The fission yeast Mcs6-Mcs2-Pmh1 complex (homologous to metazoan Cdk7-cyclin HMat1) performs dual functions: in cell cycle control, as a CDK-activating kinase; and in transcription by RNA polymerase (Pol) II, as part of TFIIH. It is unknown whether that linkage serves to coordinate gene expression w...
ORGANISM(S): Schizosaccharomyces pombe 
2004-11-01 | E-MEXP-193 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast timecourse pmh1 mutant
The fission yeast Mcs6-Mcs2-Pmh1 complex (homologous to metazoan Cdk7-cyclin HMat1) performs dual functions: in cell cycle control, as a CDK-activating kinase; and in transcription by RNA polymerase (Pol) II, as part of TFIIH. It is unknown whether that linkage serves to coordinate gene expression w...
ORGANISM(S): Schizosaccharomyces pombe 
2004-11-01 | E-MEXP-191 | biostudies-arrayexpress
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