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TranscriptomicsTranscription profiling of human peripheral blood to detect cardiac allograft rejection and response to immunosuppressive therapy
BACKGROUND: Assessment of gene expression in peripheral blood may provide a noninvasive screening test for allograft rejection. We hypothesized that changes in peripheral blood expression profiles would correlate with biopsy-proven rejection and would resolve after treatment of rejection episodes. M...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5967 | biostudies-arrayexpress
TranscriptomicsAnalysis of genomic instability in esophageal squamous cell carcinoma (ESCC)
To characterize genomic instability in esophageal squamous cell carcinoma, we examined loss of heterozygosity, copy number loss, and copy number gain in ESCC patients from a high-risk region of China. Affymetrix SNP arrays were performed according to the manufacturer's directions on DNA extracted fr...
ORGANISM(S): Homo sapiens 
2010-04-10 | E-GEOD-15526 | biostudies-arrayexpress
TranscriptomicsSpaceflight Modulates Gene Expression in Astronauts
Astronauts are exposed to a unique combination of stressors during spaceflight, which leads to alterations in their physiology and potentially increases their susceptibility to infectious pathogens. Here we report the first microarray evaluation of any astronaut tissue sample, specifically whole bl...
ORGANISM(S): Homo sapiens 
2013-10-15 | E-GEOD-47126 | biostudies-arrayexpress
TranscriptomicsThe effect of inhaled IFNbeta (SNG001) versus placebo on peripheral blood mononuclear cells during an upper respiratory tract infection
Microarray analysis of whole blood samples (collected into PAXgene tubes from PreAnalytiX) during a phase II double-blind, randomized (1:1 ratio) clinical trial in which inhaled IFN-β (SNG001) or placebo treatment was initiated within 24 hours of asthmatics reporting cold symptoms. Patients were dos...
ORGANISM(S): Homo sapiens 
2014-06-30 | E-GEOD-50943 | biostudies-arrayexpress
TranscriptomicsHuman whole blood microarray study to compare patients with tuberculosis, sarcoidosis, pneumonia, and lung cancer (validation)
This study used whole blood transcriptional signatures from patients with tuberculosis, sarcoidosis and healthy controls. There were 8 TB, 11 sarcoidosis and 23 healthy controls
ORGANISM(S): Homo sapiens 
2013-10-31 | E-GEOD-42825 | biostudies-arrayexpress
TranscriptomicsHuman whole blood microarray study to compare patients with tuberculosis, sarcoidosis, pneumonia, and lung cancer (sarcoidosis)
This study used whole blood transcriptional signatures from patients with sarcoidosis before and during immunosuppressive treatment There were 7 pneumonia patients, the same patients were sampled before and after their treatment
ORGANISM(S): Homo sapiens 
2013-10-31 | E-GEOD-42831 | biostudies-arrayexpress
TranscriptomicsHuman whole blood microarray study to compare patients with tuberculosis, sarcoidosis, pneumonia, and lung cancer (pneumonia treated)
This study used whole blood transcriptional signatures from patients with pneumonia before and after succesful antibiotic treatment There were 5 pneumonia patients, the same patients were sampled before and after their treatment
ORGANISM(S): Homo sapiens 
2013-10-31 | E-GEOD-42827 | biostudies-arrayexpress
TranscriptomicsHuman whole blood microarray study to compare patients with tuberculosis, sarcoidosis, pneumonia, and lung cancer (test)
This study used whole blood transcriptional signatures from patients with tuberculosis compared to those with similar pulmonary diseases, sarcoidosis, pneumonia and primary lung cancer. TB and sarcoidosis had similar signatures that were distinct from pneumonia and lung cancer. There were 11 TB, 25 ...
ORGANISM(S): Homo sapiens 
2013-10-31 | E-GEOD-42826 | biostudies-arrayexpress
TranscriptomicsHuman whole blood microarray study to compare patients with tuberculosis, sarcoidosis, pneumonia, and lung cancer (training)
This study used whole blood transcriptional signatures from patients with tuberculosis compared to those with similar pulmonary diseases, sarcoidosis, pneumonia and primary lung cancer. TB and sarcoidosis had similar signatures that were distinct from pneumonia and lung cancer. There were 16 TB, 25 ...
ORGANISM(S): Homo sapiens 
2013-10-31 | E-GEOD-42830 | biostudies-arrayexpress
UnknownIntegrating natural and engineered genetic variations to decode regulatory influence on blood traits.
Not available
S-EPMC12932927 | biostudies-literature
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