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MetabolomicsPostoperative Metabolic Phenoreversion in Clear Cell Renal Cell Carcinoma

The ultimate goal of surgical treatment in cancer is to remove the tumor mass for restoring a healthy state. A 16-lipid panel that discriminated healthy controls from clear cell renal cell carcinoma (ccRCC) patients in a prior study was evaluated in the present work in paired-serum samples collec...

2023-01-02 | MTBLS3838 | MetaboLights
MetabolomicsCoupled Mass-Spectrometry-Based Lipidomics Machine Learning Approach for Early Detection of Clear Cell Renal Cell Carcinoma

A discovery-based lipid profiling study of serum samples from a cohort that included patients with clear cell Renal Cell Carcinoma (ccRCC) stage I, II, III, and IV (n=112) and controls (n=52) was performed using ultraperformance liquid chromatography coupled to quadrupole-time-of-flight mass spec...

2020-11-20 | MTBLS1839 | MetaboLights
MetabolomicsMetabolomics revealed the influence of breast cancer on lymphatic endothelial cell metabolism, metabolic crosstalk, and lymphangiogenic signaling in co-culture

Breast cancer metastasis occurs via blood and lymphatic vessels. Breast cancer cells 'educate' lymphatic endothelial cells (LECs) to support tumor vascularization and growth. However, despite known metabolic alterations in breast cancer, it remains unclear how lymphatic endothelial cell metabolis...

2024-06-25 | MTBLS859 | MetaboLights
ProteomicsData for the Blood Proteoform Atlas:DS-42:T-cell:Peripheral Blood
Human biology is tightly linked to proteins, yet most measurements do not precisely determine their full sequence and post-translational modifications. Here, we present the primary structures of 30,000 unique proteoforms expressed from 1,690 human genes across 21 cell types and plasma from human blo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD026149 | Pride
Bpa Top-down proteomics Blood cell types Plasma 
ProteomicsData for the Blood Proteoform Atlas:DS-32:B Cell:Peripheral Blood
Human biology is tightly linked to proteins, yet most measurements do not precisely determine their full sequence and post-translational modifications. Here, we present the primary structures of 30,000 unique proteoforms expressed from 1,690 human genes across 21 cell types and plasma from human blo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD026143 | Pride
Bpa Top-down proteomics Blood cell types Plasma 
ProteomicsData for the Blood Proteoform Atlas:DS-52:T-cell:Peripheral Blood
Human biology is tightly linked to proteins, yet most measurements do not precisely determine their full sequence and post-translational modifications. Here, we present the primary structures of 30,000 unique proteoforms expressed from 1,690 human genes across 21 cell types and plasma from human blo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD026158 | Pride
Bpa Top-down proteomics Blood cell types Plasma 
ProteomicsData for the Blood Proteoform Atlas:DS-51:T-cell:Peripheral Blood
Human biology is tightly linked to proteins, yet most measurements do not precisely determine their full sequence and post-translational modifications. Here, we present the primary structures of 30,000 unique proteoforms expressed from 1,690 human genes across 21 cell types and plasma from human blo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD026157 | Pride
Bpa Top-down proteomics Blood cell types Plasma 
ProteomicsData for the Blood Proteoform Atlas:DS-05:T-cell:Peripheral Blood
Human biology is tightly linked to proteins, yet most measurements do not precisely determine their full sequence and post-translational modifications. Here, we present the primary structures of 30,000 unique proteoforms expressed from 1,690 human genes across 21 cell types and plasma from human blo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD026127 | Pride
Bpa Top-down proteomics Blood cell types Plasma 
ProteomicsData for the Blood Proteoform Atlas:DS-29:B Cell:Peripheral Blood
Human biology is tightly linked to proteins, yet most measurements do not precisely determine their full sequence and post-translational modifications. Here, we present the primary structures of 30,000 unique proteoforms expressed from 1,690 human genes across 21 cell types and plasma from human blo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD026140 | Pride
Bpa Top-down proteomics Blood cell types Plasma 
ProteomicsData for the Blood Proteoform Atlas:DS-33:B Cell:Peripheral Blood
Human biology is tightly linked to proteins, yet most measurements do not precisely determine their full sequence and post-translational modifications. Here, we present the primary structures of 30,000 unique proteoforms expressed from 1,690 human genes across 21 cell types and plasma from human blo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD026144 | Pride
Bpa Top-down proteomics Blood cell types Plasma 
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