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Analysis of cerebrospinal fluid (CSF) is important for diagnosis of neurological diseases. Specific proteins, which are released from the CNS can be quantitatively monitored. Especially, in the field of neurodegenerative diseases abnormal protein abundance is an important biomarker. However, the qua...
ORGANISM(S): Homo sapiens (Human) 
2020-02-17 | PXD014515 | Pride
The discovery of fetal mRNA transcripts in maternal circulation holds great promise for noninvasive prenatal diagnosis. To identify potential fetal biomarkers, we studied whole blood and plasma transcripts common to term pregnant women and their newborns but reduced or absent in the postpartum mothe...
ORGANISM(S): Homo sapiens 
Circulating blood proteomics enables minimally invasive biomarker discovery. Nanoparticle-based circulating plasma proteomics studies have reported varying number of proteins (ca 2000-7000), but it’s unclear whether higher protein number is more informative. Here, we first develop OmniProt – a silic...
ORGANISM(S): Homo sapiens (Human) 
2025-12-12 | PXD068107 | Pride
Blood was extracted from embryonic hearts at E4 and E6 and non-red blood was separated by density gradient centrifugation Experiment Overall Design: There are a total of 9 samples which have one biological replicate each, except negative control E6 embryonic heart (used to screen heart contamination...
ORGANISM(S): Gallus gallus 
Stromal contamination is one of the major confounding factors in the analysis of primary solid tumor samples by single nucleotide polymorphism (SNP) arrays. As we propose to employ genome-wide SNP microarray analysis as a diagnostic platform for neuroblastoma, the sensitivity, specificity, and accur...
ORGANISM(S): Homo sapiens 
Proteomics has been used extensively in life mechanism studies, drug target and clinical disease diagnosis, and treatment research.Several clinical surgery tissue samples inevitably get contaminated with blood during cryopreservation. This might detrimentally affect the results obtained by the comm...
ORGANISM(S): Homo Sapiens 
2021-05-10 | PXD025905 |
We have measured the proteomes of different major bovine organs in multiple replicate. Before the actual sample preparation, organs were penetrated with metal bullets experimentally. The biological material on these projectiles was then "on-surface" digested using trypsin and analyzed using LC-MS/MS...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) 
2015-11-30 | PXD002193 | Pride
Transcriptome analysis of Neisseria meningitidis strain MC58 during a time course growth in human whole blood
ORGANISM(S): Neisseria meningitidis 
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