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ProteomicsCD44 regulates epigenetic plasticity by mediating iron endocytosis - part 2
The biological process termed Epithelial-to-Mesenchymal Transition (EMT) plays a central role in cancer cell invasion, metastasis, self-renewal and resistance to therapy(1,2). Here, using western blot technique, we show that H3K9me2 decreases when MDA-MB-468 breast cancer cells undergo EMT upon EGF....
ORGANISM(S): Homo sapiens (Human) 
2010-10-09 | PXD012862 | Pride
Emt Ms/ms spectrum Histones Breast cancer 
ProteomicsThe diverse susceptibilities and responses of human and rodent cells to orthohantavirus infection reveal different levels of cellular restriction
Orthohantaviruses are rodent-borne emerging viruses known to cause severe diseases in humans but no apparent pathology in their small mammal reservoirs. However, the mechanisms leading to tolerance or pathogenicity in humans and persistence in rodent reservoirs are poorly understood, as is the manne...
ORGANISM(S): Homo sapiens (Human) 
2022-10-04 | PXD032365 | Pride
Human Orthohantavirus Restriction Rodent Infection 
ProteomicsIntegrity of the short arm of nuclear pore Y-complex is required for mouse embryonic stem cell growth and differentiation
Nuclear pore complexes (NPCs) are established players in cell division and differentiation. However studies on the contribution of individual NPC subunits to these processes are still scarce. Here we have used mouse embryonic stem cells (mESCs) to characterize the role of structural components of th...
ORGANISM(S): Mus musculus (Mouse) 
2021-05-20 | PXD022190 | Pride
Seh1 Nuclear pore Nucleoporin Cell differentiation Mouse escs Nup43 Mios Cell growth Nup85 Nuclear size 
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