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TranscriptomicsAnalysis of colorectal tissue from APC- and MYH-associated polyposis patients
Expression profiling is a well established tool for the genome-wide analysis of the transcriptional activity of human neoplasia. However, the high sensitivity of this approach combined with the well-known cellular and molecular heterogeneity of cancer often result in extremely complex and extended e...
ORGANISM(S): Homo sapiens 
2008-04-01 | E-GEOD-9689 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast to investigate the involvement of Snf7 and Rim101 in regulation of TIR1 and anaerobically up-regulated genes
Despite the scientific and applied interest in anaerobic metabolism of Saccharomyces cerevisiae, not all genes whose transcription is up-regulated under anaerobic conditions have yet been linked to known transcription factors. Experiments with a reporter construct in which the promoter of the anaero...
ORGANISM(S): Saccharomyces cerevisiae 
2009-10-02 | E-GEOD-18128 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses of yeast to preferred and non-preferred nitrogen sources in C-lim chemostat cultures
Aerobic, glucose-limited chemostat cultures of Saccharomyces cerevisiae grown with six different nitrogen sources were subjected to transcriptome analysis. The use of chemostats enabled an analysis of nitrogen-source-dependent transcriptional regulation at a fixed specific growth rate. A selection o...
ORGANISM(S): Saccharomyces cerevisiae 
2007-02-28 | E-GEOD-6405 | biostudies-arrayexpress
MetabolomicsExploring the Interspecific Interactions and the Metabolome of the Soil Isolate Hylemonella gracilis
Analysis of aquatic microbial communities revealed that parts of its diversity consist of bacteria with cell sizes of ~0.1 μm. Such bacteria can show genomic reductions and metabolic dependencies with other bacteria. So far, no study investigated if such bacteria exist in terrestrial environments e....
2022-12-14 | MTBLS5841 | MetaboLights
TranscriptomicsTemperature-dependent transcriptional response under anaerobic C and N limitations in Yeast
The global transcriptional response of Saccharomyces cerevisiae was investigated in low temperature chemostat cultures grown in carbon or nitrogen limitation. During steady state chemostats, the growth rates and in vivo fluxes were kept constant however the growth-limiting nutrient was significantly...
ORGANISM(S): Saccharomyces cerevisiae 
2007-01-20 | E-GEOD-6190 | biostudies-arrayexpress
TranscriptomicsBAC CGH array profiling using Phi29-amplified microdissected samples
Details of the experiment are available within the Nucleic Acid Research, 2004 manuscript "Genomic profiling by DNA amplification of laser capture microdissected tissues and array CGH", by Cardoso J. et al.
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-1841 | biostudies-arrayexpress
TranscriptomicsEngineering topology and kinetics of sucrose metabolism in Saccharomyces cerevisiae for improved ethanol yield
Sucrose is a major carbon source for industrial bioethanol production by Saccharomyces cerevisiae. In yeasts, two modes of sucrose metabolism occur: (i) extracellular hydrolysis by invertase, followed by uptake and metabolism of glucose and fructose, and (ii) uptake via sucrose-H+ symport followed b...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-05 | E-GEOD-30535 | biostudies-arrayexpress
UnknownNivolumab for Relapsed/Refractory Classic Hodgkin Lymphoma After Failure of Autologous Hematopoietic Cell Transplantation: Extended Follow-Up of the Multicohort Single-Arm Phase II CheckMate 205 Trial.
Not available
S-EPMC6075855 | biostudies-literature
UnknownAre Patient Expectations and Illness Perception Associated with Patient-reported Outcomes from Surgical Decompression in de Quervain's Tenosynovitis?
Not available
S-EPMC8052037 | biostudies-literature
TranscriptomicsTranscription profiling of S. cerevisiae to investigate formaldehyde as source of free-energy during growth on glucose
Previously, it has been demonstrated that formate can be utilized by Saccharomyces cerevisiae as additional energy source using cells grown in a glucose-limited chemostat. Here, we investigated utilization of formaldehyde as co-substrate. Since endogenous formaldehyde dehydrogenase activities were i...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-18 | E-GEOD-8902 | biostudies-arrayexpress
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