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UnknownLats1 and Lats2 are required for ovarian granulosa cell fate maintenance.
Not available
S-EPMC6766663 | biostudies-literature
UnknownWNT5a is required for normal ovarian follicle development and antagonizes gonadotropin responsiveness in granulosa cells by suppressing canonical WNT signaling.
Not available
S-EPMC4799500 | biostudies-literature
TranscriptomicsEither Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in ovary and testis
Stable activation of the WNT signaling effector beta-catenin (CTNNB1(ex3) in ovarian granulosa cells results in the formation of premalignant lesions that develop into granulosa cell tumors (GCTs) spontaneously later in life. Loss of the tumor suppressor gene Pten accelerates GCT formation in the CT...
ORGANISM(S): Mus musculus 
2011-09-19 | E-GEOD-27656 | biostudies-arrayexpress
TranscriptomicsSeminiferous tubule degeneration and infertility in mice with sustained activation of WNT/CTNNB1 signaling in sertoli cells
To elucidate the role(s) of WNT/CTNNB1 signaling in the testis, transgenic Ctnnb1 tm1Mmt/+;Amhr2 tm3(cre)Bhr/+ mice were generated to obtain sustained activation of the WNT/CTNNB1 pathway in Sertoli cells. Male Ctnnb1 tm1Mmt/+;Amhr2 tm3(cre)Bhr/+ mice were sterile because of testicular atrophy start...
ORGANISM(S): Mus musculus 
2011-04-05 | E-GEOD-28402 | biostudies-arrayexpress
UnknownSlit/Robo signaling regulates Leydig cell steroidogenesis.
Not available
S-EPMC7819258 | biostudies-literature
UnknownChanges in participatory and societal outcomes during the waiting period for cochlear implantation - an observational study.
Not available
S-EPMC11805756 | biostudies-literature
UnknownPostoperative management of total elbow arthroplasty: Results of a European survey among orthopedic surgeons.
Not available
S-EPMC9662720 | biostudies-literature
UnknownThe granulosa cell response to luteinizing hormone is partly mediated by YAP1-dependent induction of amphiregulin.
Not available
S-EPMC9137176 | biostudies-literature
UnknownNon-canonical WNT5a regulates Epithelial-to-Mesenchymal Transition in the mouse ovarian surface epithelium.
Not available
S-EPMC7298016 | biostudies-literature
UnknownTargeted Disruption of YAP and TAZ Impairs the Maintenance of the Adrenal Cortex.
Not available
S-EPMC5695830 | biostudies-literature
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