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Signal transducer and activator of transcription 3 (STAT3) is altered in several epithelial cancers and represents a potential therapeutic target. Here, STAT3 expression, activity and cellular functions were examined in two main histotypes of esophageal carcinomas. In situ, immunohistochemistry for ...
ORGANISM(S): Homo sapiens 
Transcription profiling of Physcomitrella patens leaflet timeseries
ORGANISM(S): Physcomitrella patens 
The thorough characterization of the transcriptome of endogenous podocytes has been hampered by low yields of cell isolation procedures. Here we introduce a double fluorescent reporter mouse model combined with an optimized bead perfusion protocol and efficient single cell dissociation yield...
ORGANISM(S): Mus musculus 
Purpose: Next-generation sequencing (NGS) was used to define the transcriptome of native mouse podocytes and non-podocytes glomerular cells as part of a project aiming to define the molecular fingerprint of mouse podocytes. Method: Glomeruli from 29 Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/J x hNPHS...
ORGANISM(S): Mus musculus 
Label-free expression proteomics analysis of FACS-sorted mouse podocytes versus non-podocytes
ORGANISM(S): Mus musculus (Mouse) 
2018-12-14 | PXD010601 | Pride
We identified binding sites of the Wilms' tumor suppressor protein WT1 in the mouse podocyte genome in vivo by ChIP-seq. Furthermore, we provide a podocyte transcriptome derived from primary podocytes that were isolated by FACS on mouse glomeruli. In short, we show that WT1 activates a highly specif...
ORGANISM(S): Mus musculus 
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