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MetabolomicsIdentification of BolA protein reveals a novel virulence factor in Klebsiella pneumoniae that contributes to liver abscess in mice

BolA has been characterized as an important transcriptional regulator, which is induced in the stationary phase of growth and is often associated with bacterial virulence. This study was initiated to elucidate the role of the BolA in the virulence of K. pneumoniae. Using a mous...

2022-09-13 | MTBLS2712 | MetaboLights
TranscriptomicsBolA is a transcriptional switch that turns off motility and turns on biofilm development
Bacteria are extremely versatile organisms which rapidly adapt to changing environments. When Escherichia coli cells switch from planktonic growth to biofilm, flagellum formation is turned off, and the production of fimbriae and extracellular polysaccharides is switched on. Here we show that BolA pr...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2015-02-19 | E-GEOD-58509 | biostudies-arrayexpress
GenomicsBolA is a transcriptional switch that turns off motility and turns on biofilm development (ChIP-seq)
Bacteria are extremely versatile organisms which rapidly adapt to changing environments. When Escherichia coli cells switch from planktonic growth to biofilm, flagellum formation is turned off, and the production of fimbriae and extracellular polysaccharides is switched on. Here we show that BolA pr...
ORGANISM(S): Escherichia coli 
2015-02-19 | E-GEOD-58623 | biostudies-arrayexpress
ProteomicsAnalysis of bovine leukocyte antigen (BoLA)-associated peptides by LC-MS
An increasing amount of MHC presented peptides identified by mass spectrometry (MS ligands) has been published. Handling and interpretation of MS ligand data is in general challenging due to the poly-specificity nature of the data. We here outline a general pipeline for dealing with this challenge,...
ORGANISM(S): Bos taurus (Bovine) 
2017-11-20 | PXD008151 | Pride
Immunopeptidomics Bola 
ProteomicsBoLA-DRimmunopeptidomics in Theileria parva infected, bovine cell lines
The ability to maintain T.parva-infected cell lines as rapidly proliferating cells in vitro that express high levels of both MHCI and MHCII, makes this a particularly amenable system in which to apply MHCp elution analysis. Furthermore, the ability of T. parva-infected cells to recall antigen-specif...
ORGANISM(S): Bos taurus (Bovine) 
2022-05-19 | PXD024053 | Pride
Immunppeptidomics Bovine leukocyte antigen  theileria parva  mhc 
TranscriptomicsBolA is a transcriptional switch that turns off motility and turns on biofilm development
Bacteria are extremely versatile organisms which rapidly adapt to changing environments. When Escherichia coli cells switch from planktonic growth to biofilm, flagellum formation is turned off, and the production of fimbriae and extracellular polysaccharides is switched on. Here we show that BolA pr...
ORGANISM(S): Escherichia coli Escherichia coli str. K-12 substr. MG1655 
2015-02-19 | GSE58509 | GEO
GenomicsBolA is a transcriptional switch that turns off motility and turns on biofilm development (ChIP-seq)
Bacteria are extremely versatile organisms which rapidly adapt to changing environments. When Escherichia coli cells switch from planktonic growth to biofilm, flagellum formation is turned off, and the production of fimbriae and extracellular polysaccharides is switched on. Here we show that BolA pr...
ORGANISM(S): Escherichia coli 
2015-02-19 | GSE58623 | GEO
UnknownImmunopeptidomic Analysis of BoLA-I and BoLA-DR Presented Peptides from Theileria parva Infected Cells.
Not available
S-EPMC9699068 | biostudies-literature
UnknownRegulation of BolA abundance mediates morphogenesis in Fremyella diplosiphon.
Not available
S-EPMC4633512 | biostudies-literature
UnknownStructural and spectroscopic insights into BolA-glutaredoxin complexes.
Not available
S-EPMC4148882 | biostudies-literature
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