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TranscriptomicsTranscriptional responses of mouse bone marrow-derived macrophages (BMM) to lipopolysaccharide (LPS) - Illumina arrays
These microarrays were performed for use in a genome-wide scan for LPS-regulated genes in mouse macrophages, in order to construct a list of LPS-regulated genes for detailed interrogation on custom microarrays (see GSE19490 for custom array analysis). Mouse macrophages (bone marrow-derived macrophag...
ORGANISM(S): Mus musculus 
2012-03-28 | E-GEOD-19766 | biostudies-arrayexpress
TranscriptomicsConservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages
This SuperSeries is composed of the following subset Series: GSE19482: Transcriptional responses of human monocyte-derived macrophages (HMDM) to lipopolysaccharide (LPS) GSE19490: Transcriptional responses of mouse BMM and TEPM to lipopolysaccharide (LPS) GSE19765: Transcriptional responses of human...
ORGANISM(S): Mus musculus 
2012-03-28 | E-GEOD-19492 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses of mouse BMM and TEPM to lipopolysaccharide (LPS)
Evolutionary change in gene expression is generally considered to be a major driver of phenotypic differences between species. We investigated innate immune diversification by analyzing inter-species differences in the transcriptional responses of primary human and mouse macrophages to the TLR4 agon...
ORGANISM(S): Mus musculus 
2012-03-28 | E-GEOD-19490 | biostudies-arrayexpress
TranscriptomicsDifferentiation of human monocytes to macrophages in the presence of GM-CSF +/- forskolin (FSK)
Macrophages are central mediators of the innate immune system that can be differentiated from monocytes upon exposure to cytokines. While increased cyclic adenosine monophosphate (cAMP) levels inhibit many lipopolysaccharide (LPS) -elicited macrophage inflammatory responses, the effects of elevated ...
ORGANISM(S): Homo sapiens 
2010-06-20 | E-GEOD-18654 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses of human monocyte-derived macrophages (HMDM) to lipopolysaccharide (LPS)
Evolutionary change in gene expression is generally considered to be a major driver of phenotypic differences between species. We investigated innate immune diversification by analyzing inter-species differences in the transcriptional responses of primary human and mouse macrophages to the TLR4 agon...
ORGANISM(S): Homo sapiens 
2012-03-28 | E-GEOD-19482 | biostudies-arrayexpress
UnknownDevelopment and Functional Characterization of Murine Tolerogenic Dendritic Cells.
Not available
S-EPMC6101271 | biostudies-literature
TranscriptomicsTranscriptional responses of human monocyte-derived macrophages (HMDM) to lipopolysaccharide (LPS) - Illumina arrays
These microarrays were performed for use in a genome-wide scan for LPS-regulated genes in human monocyte-derived macrophages, in order to construct a list of LPS-regulated genes for detailed interrogation on custom microarrays (see GSE19482 for custom array analysis). Human monocyte-derived macropha...
ORGANISM(S): Homo sapiens 
2012-03-28 | E-GEOD-19765 | biostudies-arrayexpress
MetabolomicsMicrobial-derived 3-phenylpropionic acid orchestrates immune–progenitor cell crosstalk to promote beige adipogenesis and energy expenditure

Cold exposure induces beige adipogenesis in white adipose tissue (iWAT), enhancing thermogenesis and energy expenditure. While gut microbiota-derived metabolites are known to regulate host metabolism, their role in thermogenic adaptation remains poorly defined. Here, we identify Prevotella copri ...

2025-12-13 | MTBLS13503 | MetaboLights
TranscriptomicsComparative gene expression analysis of dental follicle and periodontal ligament in humans
The aim of this study was to evaluate and compare the gene expression profiles of dental follicle and periodontal ligament in humans, which can possibly explain their functions of dental follicle and PDL such as eruption coordination and stress resorption. That may apply this information to clinical...
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-51342 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver to identify gene expression associated with Strain-Specific Ehrlichia chaffeensisa induced Hepatitis
Infection of humans with Ehrlichia chaffeensis, the etiologic agent of human monocytic ehrlichiosis, can cause hepatitis of varying severity. When the three human isolates of E. chaffeensis, each belongs to different geno-groups, are inoculated into severe combined immunodeficiency mice, the severit...
ORGANISM(S): Mus musculus 
2009-08-22 | E-GEOD-8966 | biostudies-arrayexpress
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