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The gene expression of bone marrow cells of mice enriched for Gremlin1 vs control was measured (n=3). It is not known if endogenous adult mesenchymal stem cells (MSCs) exist.Following culture,perisinusoidal mesenchymal cells can clonally recapitulate the skeletal microenvironment, but this fails to ...
ORGANISM(S): Mus musculus 
Lu H, Clauser KR, Tam WL, Fröse J, Ye X, Eaton EN, Reinhart F, Donnenberg VS, Bhargava R, Carr SA, Weinberg RA, Nature Cell Biol 2014 in press
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-08-04 | MSV000078799 | MassIVE
To compare human memory CD4+ T cell subsets in peripheral blood (PB) and bone marrow (BM) of healthy individuals at transcriptional level, we analyzed the global gene expression of ex vivo PB CD69- as well as BM CD69- and CD69+ memory CD4+ T cells from 4 paired PB and BM samples. The gene expression...
ORGANISM(S): Homo sapiens 
Rheumatoid arthritis is a prototypical autoimmune arthritis affecting nearly 1% of the world population and is a significant cause of worldwide disability. Though prior studies have demonstrated the appearance of RA-related autoantibodies years before the onset of clinical RA, the pattern of immunol...
ORGANISM(S): Homo sapiens 
Rheumatoid arthritis is a prototypical autoimmune arthritis affecting nearly 1% of the world population and is a significant cause of worldwide disability. Though prior studies have demonstrated the appearance of RA-related autoantibodies years before the onset of clinical RA, the pattern of immunol...
ORGANISM(S): Homo sapiens 
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