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TranscriptomicsCTL-OA-OP human IT PF Bone - CompuGen H19K microarray study
Aims of study: (1) To identify systemic differences in osteoarthritic (OA) bone that contribute to OA pathogenesis. (2) Identify novel osteoporotic (OP) bone-related disease genes. Study involved comparison of trabecular bone extracted from the intertrochanteric (IT) region of the proximal femur (PF...
ORGANISM(S): Homo sapiens 
2008-01-14 | E-GEOD-8406 | biostudies-arrayexpress
ModelsLiò2012_Modelling osteomyelitis_Control Model
Background This work focuses on the computational modelling of osteomyelitis, a bone pathology caused by bacteria infection (mostly Staphylococcus aureus). The infection alters the RANK/RANKL/OPG signalling dynamics that regulates osteoblasts and osteoclasts behaviour in bone remodelling, i.e. the r...
2024-09-02 | BIOMD0000000923 | BioModels
TranscriptomicsImpaired Chromatin Remodelling at STAT1-Regulated Promoters Leads to Global Unresponsiveness of Toxoplasma gondii-Infected Macrophages to IFN-Gamma
Intracellular pathogens including the apicomplexan and opportunistic parasite Toxoplasma gondii profoundly modify their host cells in order to establish infection. We have shown previously that intracellular T. gondii inhibit up-regulation of regulatory and effector functions in murine macrophages (...
ORGANISM(S): Mus musculus 
2012-01-25 | E-GEOD-28499 | biostudies-arrayexpress
UnknownDevelopment of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts.
Not available
S-EPMC6884811 | biostudies-literature
UnknownModelling osteomyelitis.
Not available
S-EPMC3439679 | biostudies-literature
UnknownIdentification of mechanics-responsive osteocyte signature in osteoarthritis subchondral bone.
Not available
S-EPMC9233409 | biostudies-literature
UnknownThe effect of age on the microarchitecture and profile of gene expression in femoral head and neck bone from patients with osteoarthritis.
Not available
S-EPMC7292911 | biostudies-literature
UnknownConditional deletion of E11/Podoplanin in bone protects against ovariectomy-induced increases in osteoclast formation and activity.
Not available
S-EPMC6954370 | biostudies-literature
TranscriptomicsTranscription profiling of fission yeast at different time points after the start of glucose starvation identifies stepwise chromatin remodeling by a cascade of transcription initiation of non-coding RNAs
Recent transcriptome analyses using high-density tiling arrays and data from large-scale analyses of full-length cDNA libraries by the FANTOM3 consortium reveal that many transcripts are non-coding RNAs (ncRNAs). These transcriptome analyses indicate that many of the non-coding regions, previously t...
ORGANISM(S): Schizosaccharomyces pombe 
2008-09-28 | E-MEXP-1747 | biostudies-arrayexpress
UnknownDynamic assessment of a humanized bone tumour microenvironment reveals insights into osteosarcoma primary tumour remodelling and lung metastases.
Not available
S-EPMC12753712 | biostudies-literature
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