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ProteomicsTwo step enrichment facilitates background reduction for proteomic analysis of lysosomes
Lysosomes comprise the main degradative compartment of almost all mammalian cells and are involved in various cellular functions, most of which are catalyzed by the lysosomal proteome. Lysosomal proteins are low abundant, complicating their analysis by mass spectrometry-based proteomics. To increase...
ORGANISM(S): Homo sapiens (Human) 
2024-08-01 | PXD048696 | Pride
Lysosomes  lysosome enrichment  superparamagnetic iron oxide particles (spions)  tmem192 Mass spectrometry  proteomics  organelles Hek 293 
ProteomicsFractionated proteomics identifies a protein network mitigating resistance exercise-induced damage in human skeletal muscle
Resistance exercise (RE) improves strength and muscle mass, with multiple benefits for human health. However, intense RE also induces acute myofibrillar damage. The molecular mechanisms that preserve, mark, degrade and restore damaged proteins in order to to keep skeletal muscle working under RE are...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-04 | PXD074000 | Pride
ProteomicsCapture and functional conversion of mitochondrial protein translocase by lipid metabolism enzyme
Capture and functional conversion of mitochondrial protein translocase by lipid metabolism enzyme
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-01-22 | PXD070899 | Pride
Lipid Proteomics Mitochondria Translocase Yeast 
ProteomicsCapture and functional conversion of mitochondrial protein translocase by lipid metabolism enzyme
Capture and functional conversion of mitochondrial protein translocase by lipid metabolism enzyme
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae (Baker's yeast) 
2026-01-22 | PXD062073 | Pride
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