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TranscriptomicsA critical role of microRNAs in human pulmonary arterial hypertension. miR-204: a novel therapeutic target (TaqMan qPCR)
Pulmonary arterial hypertension (PAH) is a vascular remodeling disease characterized by enhanced pulmonary artery smooth muscle cell (PASMC) proliferation and suppressed apoptosis. Downregulation of the BMPR2 gene along with activation of the transcription factor NFAT have been implicated in the mai...
ORGANISM(S): Homo sapiens 
2010-12-16 | E-GEOD-21281 | biostudies-arrayexpress
GenomicsThe SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription [Yeast cells]
The SAGA co-activator complex contains distinct chromatin-modifying activities and is recruited by DNA-bound activators to regulate the expression of a subset of genes. Surprisingly, recent studies revealed little overlap between genome-wide SAGA-binding profiles and changes in gene expression upon ...
ORGANISM(S): Saccharomyces cerevisiae 
2014-08-29 | E-GEOD-52997 | biostudies-arrayexpress
GenomicsThe SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription [HeLa cells]
The SAGA co-activator complex contains distinct chromatin-modifying activities and is recruited by DNA-bound activators to regulate the expression of a subset of genes. Surprisingly, recent studies revealed little overlap between genome-wide SAGA-binding profiles and changes in gene expression upon ...
ORGANISM(S): Homo sapiens 
2014-08-29 | E-GEOD-52860 | biostudies-arrayexpress
UnknownBinding to RNA regulates Set1 function.
Not available
S-EPMC5654745 | biostudies-literature
UnknownImpact of early mean arterial pressure level on severe acute kidney injury occurrence after out-of-hospital cardiac arrest.
Not available
S-EPMC9288937 | biostudies-literature
UnknownEfficacy of extracranial stereotactic body radiation therapy (SBRT) added to standard treatment in patients with solid tumors (breast, prostate and non-small cell lung cancer) with up to 3 bone-only metastases: study protocol for a randomised phase III trial (STEREO-OS).
Not available
S-EPMC7863429 | biostudies-literature
UnknownAseptic Abscess Syndrome: Clinical Characteristics, Associated Diseases, and up to 30 Years' Evolution Data on a 71-Patient Series.
Not available
S-EPMC9267245 | biostudies-literature
UnknownValidation of the Valve Academic Research Consortium High Bleeding Risk Definition in Patients Undergoing TAVR.
Not available
S-EPMC11748903 | biostudies-literature
UnknownTobacco, alcohol, cannabis, and illicit drug use and their association with CD4/CD8 cell count ratio in people with controlled HIV: a cross-sectional study (ANRS CO3 AQUIVIH-NA-QuAliV).
Not available
S-EPMC9830769 | biostudies-literature
UnknownST-segment elevation myocardial infarction: Management and association with prognosis during the COVID-19 pandemic in France.
Not available
S-EPMC9056233 | biostudies-literature
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