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ProteomicsA combined N-terminomics and shotgun proteomics approach to investigate the responses of human cells to rapamycin and zinc at the mitochondrial level
This study aims at investigating the impact of rapamycin and zinc at subtoxic doses on the human mitochondrial proteome. Experiments were performed on U397 monocytic cells. A dN-TOP strategy, combining shotgun proteomics and N-terminomics, was applied to study both internal and N-terminal peptides o...
ORGANISM(S): Homo sapiens (Human) 
2019-05-14 | PXD010220 | Pride
N-terminome analysis Mitochondria Nanolc-ms/ms Dn-top strategy Differential analysis 
ProteomicsA combined N-terminomics and shotgun proteomics approach to investigate the responses of human cells to rapamycin and zinc at the mitochondrial level
This study aims investigating the impact of rapamycin and zinc at subtoxic doses on the human mitochondrial proteome. Experiments were performed on U397 monocytic cells. A dN-TOP strategy, combining shotgun proteomics and N-terminomics, was applied to study both internal and N-terminal peptides of t...
ORGANISM(S): Homo sapiens (Human) 
2019-05-14 | PXD010572 | Pride
N-terminome analysis Mitochondria Nanolc-ms/ms Dn-top strategy Differential analysis 
ProteomicsCombining label-free and label-based accurate quantifications with SWATH-MS: comparison with SRM and PRM for the evaluation of bovine muscle type effects
The performances of label-based SWATH-MS, SRM and PRM to accurately quantify ten candidate biomarkers of beef meat tenderness or marbling, in a cohort of 64 bovine muscle tissues expected to cover a wide biological range of these traits, were evaluated. Limits of quantification, dynamic range and qu...
ORGANISM(S): Bos taurus (Bovine) 
2021-06-09 | PXD020638 | Pride
Beef meat quality  data-independent acquisition (dia)  quantitative ms  swath-ms  targeted proteomics 
ProteomicsCombining label-free and label-based accurate quantifications with SWATH-MS: comparison with SRM and PRM for the evaluation of bovine muscle type effects.
Mass spectrometry has proven to be a valuable tool for the accurate quantification of proteins. In this study, we have evaluated the performances of three targeted approaches, namely Selected Reaction Monitoring (SRM), Parallel Reaction Monitoring (PRM) and Sequential Windowed Acquisition of Theoret...
ORGANISM(S): Bos Taurus 
2021-06-08 | PXD020680 | panorama
ProteomicsData-Independent Acquisitions Uncover Kidney Proteome Remodeling during Ischemic Reperfusion Kidney Injury using a Fast-scanning ZenoTOF 7600
Acute kidney injury (AKI) manifests as a major health concern particularly for the elderly and understanding related proteome changes is critical for prevention and development of novel therapeutics to recover kidney function, and to mitigate the susceptibility for recurrent AKI, or development of c...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-11-23 | MSV000090777 | MassIVE
UnknownSenescent Schwann cells induced by aging and chronic denervation impair axonal regeneration following peripheral nerve injury
Not available
S-SCDT-10_15252-EMMM_202317907 | biostudies-other
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