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TranscriptomicsGene Expression Arrays comparing wild-type Kluyveromyces lactis a, alpha, and a/alpha cells and a comparison between WT a cells and rme1 knock-out a cells
WT and rme1 KO K. lactis cells (a, alpha, and a/alpha) were grown in YEPD, phosphate starvation and phosphate starvation with the addition of alpha pheromone. The goal was to identify cell-type regulated genes and to determine the effects of growth media on the regulation of cell-type regulated gene...
ORGANISM(S): Kluyveromyces lactis 
2010-12-01 | E-GEOD-24874 | biostudies-arrayexpress
TranscriptomicsInducible expression of PrPC in mouse skeletal muscles results in myopathy characterized by changes in gene expression
Over-expression of wild type PrP in skeletal muscles is sufficient to cause a primary myopathy with no signs of peripheral neuropathy, possibly due to accumulation of a cytotoxic truncated form of PrP and/or PrP aggregation. In this study we used DNA microarrays to identify 1499 transcripts that ar...
ORGANISM(S): Mus musculus 
2008-08-27 | E-GEOD-12576 | biostudies-arrayexpress
GenomicsGenome-wide distribution of 5-formylcytosine in ES cells is associated with transcription and depends on TDG
Methylation of cytosine in DNA (5mC) is an important epigenetic mark that is involved in the regulation of genome function. During early embryonic development in mammals, the DNA methylation landscape is dynamically reprogrammed in part through active demethylation. Recent advances have identified k...
ORGANISM(S): Mus musculus 
2012-08-17 | E-GEOD-40148 | biostudies-arrayexpress
UnknownSIMULTANEOUS LIVER KIDNEY TRANSPLANTATION IN LIVER TRANSPLANT CANDIDATES WITH RENAL DYSFUNCTION: IMPORTANCE OF CREATININE LEVELS, DIALYSIS, AND ORGAN QUALITY IN SURVIVAL.
Not available
S-EPMC5138564 | biostudies-literature
ProteomicsProteomic analysis of outer membrane vesicle isolation methods with an Escherichia coli tolA mutant using LC MSMS
Outer membrane vesicles (OMVs) produced by Gram-negative bacteria are mediators of cell survival and pathogenesis by facilitating nutrient transport, virulence factor dissemination, and resistance to antimicrobials. Studies of OMV properties often focus on hypervesiculating Escherichia coli mutants ...
ORGANISM(S): Escherichia coli 
2021-09-09 | PXD022786 | Pride
Lc-msms Escherichia coli Omv Tola 
UnknownCirculating Phylloquinone Concentrations and Risk of Type 2 Diabetes: A Mendelian Randomization Study.
Not available
S-EPMC6314462 | biostudies-literature
UnknownCost-effectiveness of supported self-management for CFS/ME patients in primary care.
Not available
S-EPMC3556109 | biostudies-literature
TranscriptomicsGene expression arrays comparing Kluyveromyces lactis wild-type a cells to MATa2 knock-out a cells and wild-type alpha cells to MATalpha2 knock-out alpha cells
We examine how different transcriptional network structures can evolve from a common, ancestral network. We show that regulatory protein modularity, conversion of one cis-regulatory sequence to another, distribution of binding energy among protein-protein and protein-DNA interactions, and exploitati...
ORGANISM(S): Kluyveromyces lactis 
2012-06-29 | E-GEOD-39027 | biostudies-arrayexpress
TranscriptomicsBrain_22A-Scrapie_End-point_PR04-39-to-46_using_GPL7118
Examining the transcriptional change in whole mouse (VM) brain miRNA expression during prion (22A) induced neurodegeneration in order to identify miRNAs that are differentially expressed. MicroRNAs (miRNAs) are small, non-coding RNA molecules which are emerging as key regulators of numerous cellular...
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-12321 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human alveolar macrophages infected by B. anthracis spores
Bacillus anthracis is a gram-positive, aerobic, spore-forming, rod-shaped bacterium which has recently been used as an agent of bioterrorism. Because there is a significant delay between the initial contact of the spore with the host and clinical evidence of disease, there appears to be temporary co...
ORGANISM(S): Homo sapiens 
2009-10-16 | E-GEOD-14390 | biostudies-arrayexpress
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