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Using HDX-MS to study Rab and Ral covalently bound to MRTX1257
Here we use HDX to study covalently modified Rab1a and RalA in both their apo states and bound to MRTX1257 to see how this compound affects the overall secondary structure of the proteins.
ORGANISM(S):
Homo sapiens (Human)
2025-03-10
|
PXD041440
|
Pride
Rab
Hdx-ms
Ral
Hdx
Gtpase
Cite
Targeting Ras-, Rho-, and Rab-family GTPases via a conserved cryptic pocket.
Not available
S-EPMC11531380
|
biostudies-literature
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