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TranscriptomicsTranscription profiling of human MCF-7 breast cancer cells treated with E2, ICI 182,789 (ICI), Raloxifene (Ral), and/or trans-hydroxytamoxifen (TOT)
MCF-7 breast cancer cells were treated with E2, ICI 182,789 (ICI), Raloxifene (Ral), and/or trans-hydroxytamoxifen (TOT) for 8 or 48 h. Duplicate samples are labeled set A or set B.
ORGANISM(S): Homo sapiens 
2007-09-27 | E-GEOD-848 | biostudies-arrayexpress
GenomicsDrosophila melanogaster strain:RAL-399
The midgut transcriptome in Drosophila melanogaster inbreed line RAL-399
PRJNA647056 | ENA
GenomicsDrosophila melanogaster strain:RAL-399
The genome raw sequencing reads in Drosophila melanogaster inbreed line RAL-399 (Ssk-FB4 knock out)
PRJNA716121 | ENA
TranscriptomicsGene expression profile in a breast cancer cell line upon hormonal treatments
MCF-7 TET Off cells (MCF-7 wt) were used to produce stable clones expressing ER-alpha tagged with TAP-tag at the C-term (C-TAP-ER-alpha). All cells were grown in Dulbecco's modified Eagle's medium (DMEM), starved by using DMEM w/o phenol red and 5% Dextran Coated Charcoal stripped serum (DCC-FBS) fo...
ORGANISM(S): Homo sapiens 
2012-06-25 | E-MTAB-1196 | biostudies-arrayexpress
ProteomicsUsing HDX-MS to study Rab and Ral covalently bound to MRTX1257
Here we use HDX to study covalently modified Rab1a and RalA in both their apo states and bound to MRTX1257 to see how this compound affects the overall secondary structure of the proteins.
ORGANISM(S): Homo sapiens (Human) 
2025-03-10 | PXD041440 | Pride
Rab Hdx-ms Ral Hdx Gtpase 
ProteomicsRal GTPases promote metastasis by controlling biogenesis and organotropism of exosomes
Cancer extracellular vesicles (EVs) mainly exert pro-tumoral functions by changing the phenotypes of stromal cells to the benefit of tumor growth and metastasis. In particular, they shuttle to distant organs and seed pre-metastatic niches facilitating subsequent colonization by circulating tumor cel...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD020180 | Pride
Human Ral Nanolcmsms prostar maxquant Extracellular vesicles 
UnknownRal-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling.
Not available
S-EPMC4973806 | biostudies-literature
UnknownAffinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases.
Not available
S-EPMC7949049 | biostudies-literature
TranscriptomicsRAL GTPases mediate EGFR/MAPK signalling-driven intestinal stem cell proliferation and tumourigenesis upstream of RAS activation.
Abstract: RAS-like (RAL) GTPases function in Wnt signalling-dependent intestinal stem cell proliferation and regeneration. Whether RAL proteins work as canonical RAS effectors in the intestine, and the mechanisms of how they contribute to tumorigenesis remain unclear. Here, we show that RAL GTPases ...
ORGANISM(S): Drosophila melanogaster 
2021-02-01 | GSE162421 | GEO
TranscriptomicsTranscriptomics analysis of oligodendrocyte-enriched sorted cells with conditional deletion of Ral GTPases during development
RNA sequencing was performed to evaluate the transcriptome of oligodendrocyte-enriched sorted cells extracted from mice with conditional deletion of Ral GTPases in the oligodendrocyte-lineage during development.
ORGANISM(S): Mus musculus 
2022-09-27 | GSE180725 | GEO
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