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TranscriptomicsRNA-seq of mouse embryonic stem cells with knockout of Nhlrc2 gene or addition of FINCA disease causing NHLRC2 p.Asp148Tyr variant
Fibrosis, neurodegeneration, and cerebral angiomatosis (FINCA) (OMIM 618278) is a rare infantile-onset disease caused by variants in NHL repeat containing 2 (NHLRC2) gene. NHLRC2 is essential for mouse gastrulation (Hiltunen et al., 2022). Here, RNA sequencing was performed on four wild type (WT), f...
ORGANISM(S): Mus musculus 
2025-05-22 | E-MTAB-14174 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse wild type and Ctip2-/- (Bcl11b) mutant striatum at P0
Striatal medium spiny neurons (MSN) are critically involved in motor control, and their degeneration is a principal component of Huntington’s disease. We find that the transcription factor Ctip2 (also known as Bcl11b) is central to MSN differentiation and striatal development. Within the striatum,...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9330 | biostudies-arrayexpress
UnknownAnisotropic light propagation in human brain white matter.
Not available
S-EPMC12510258 | biostudies-literature
UnknownMyelinated fiber labeling and orientation mapping of the human brain with light-sheet fluorescence microscopy.
Not available
S-EPMC12706767 | biostudies-literature
TranscriptomicsIllumina microarray experiment on LSD1 deletion ES cell with Lsd1Lox/Δ3 and Lsd1Δ3/Δ3
Lysine specific demethylase 1 (LSD1), which demethylates mono- and di- methylated histone H3-Lys4 as part of a complex including CoREST and histone deacetylases (HDAC), is essential for embryonic development in the mouse beyond e6.5 days. Here, we demonstrate that LSD1 expression and therefore funct...
ORGANISM(S): Mus musculus 
2010-12-06 | E-GEOD-21131 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse FACS-purified cortical projection neurons using Affymetrix 430 2.0 microarrays
3 subtypes of cortical projection neurons were purified by fluorescence-activated cell sorting (FACS) at 4 different stages of development from mouse cortex. A detailed description of the data set is described in Arlotta, P et al (2005) and Molyneaux, BJ et al (2009). The hybridization cocktails use...
ORGANISM(S): Mus musculus 
2009-10-09 | E-GEOD-17783 | biostudies-arrayexpress
UnknownInfected pancreatic necrosis: outcomes and clinical predictors of mortality. A post hoc analysis of the MANCTRA-1 international study.
Not available
S-EPMC10005914 | biostudies-literature
UnknownA shared MHC supertype motif emerges by convergent evolution in macaques and mice, but is totally absent in human MHC molecules.
Not available
S-EPMC3349854 | biostudies-literature
TranscriptomicsTranscription profiling of CD146 immunomagnetically enriched circulating endothelial cells (CECs) from healthy donors and patients with metastatic breast, colorectal, prostate, lung and renal cancer
Increased numbers of endothelial cells are observed in peripheral blood of cancer patients. These circulating endothelial cells (CECs) may contribute to the formation of blood vessels in the tumor or reflect vascular damage caused by treatment or tumor growth. Characterization of these cells may a...
ORGANISM(S): Homo sapiens 
2006-11-08 | E-MEXP-476 | biostudies-arrayexpress
GenomicsBinding site turnover produces pervasive quantitative changes in TF binding between closely related Drosophila species
[original title] Binding site turnover produces pervasive quantitative changes in transcription factor binding between closely related Drosophila species. We demonstrate extensive quantitative changes in binding of six factors that control early embryonic patterning between two closely related Droso...
ORGANISM(S): Drosophila melanogaster 
2010-02-18 | E-GEOD-20369 | biostudies-arrayexpress
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