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TranscriptomicsThe Dynamic Transcriptome of Schizosaccharomyces pombe Revealed by RNA/DNA Hybrid Mapping
We determined the strand-specific transcriptome of the fission yeast S. pombe under multiple growth conditions using a novel RNA/DNA hybridization mapping (HybMap) technique. HybMap uses an antibody against an RNA/DNA hybrid to detect RNA molecules hybridized to a high density DNA oligonucleotide ti...
ORGANISM(S): Schizosaccharomyces pombe 
2008-06-29 | E-GEOD-11619 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of DNA from two recently divergent mouse strains, 12925 and C57BL/6J
We have performed CGH analysis using 129S5 DNA competitively hybridised with C57BL/6J DNA to RPCI-23 (C57BL/6J) BAC clones spotted at 1Mb resolution (array protocol 7769)
ORGANISM(S): Mus musculus 
2005-04-01 | E-MEXP-298 | biostudies-arrayexpress
GenomicsDistinctive Chromatin in Human Sperm Packages Genes that Guide Embryo Development: ChIP-seq
As nucleosomes are widely replaced by protamine in mature human sperm, epigenetic contributions to embryo development appear limited. However, our genome-wide approaches find nucleosomes at low levels genome-wide, but also significantly enriched at imprinted gene clusters, miRNA clusters, HOX gene...
ORGANISM(S): Homo sapiens 
2009-06-15 | E-GEOD-15690 | biostudies-arrayexpress
TranscriptomicsCGH analyses of human induced pluripotent stem cells
Human induced pluripotent stem cells (hIPSCs) represent a unique opportunity for regenerative medicine since they offer the prospect of generating unlimited quantities of cells for autologous transplantation as a novel treatment for a broad range of disorders. However, the use of hIPSCs in the conte...
ORGANISM(S): Homo sapiens 
2011-09-01 | E-MEXP-3316 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse ES cells, neural precursor cells and embryonic fibroblasts
Expression profiles for isogenic (129SvJae x C57BL/6) murine embryonic stem (ES) cells, neural precursors (NPC) obtained through in vitro differentiation of the ES cells, and embryonic fibroblasts (MEF) obtained at day 13.5. Experiment Overall Design: 3 replicates of wt ES cells, 3 replicates of wt...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-8024 | biostudies-arrayexpress
TranscriptomicsExon Level Expression Profiling: a Novel Unbiased Transcriptome Analysis for Body Fluids
Transcriptome analysis of partially degraded and fragmented RNA samples from body fluids Global gene expression profiling has shown great promise in high-throughput biomarker discovery for early disease detection in body fluids such as saliva, which is accessible, cost-effective, and non-invasive. ...
ORGANISM(S): Homo sapiens 
2008-05-19 | E-GEOD-7760 | biostudies-arrayexpress
ProteomicsHewings et al. 2018
raw data files associated with manuscript titled "Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes". Result file includes all PSMs identified in the experiment after performing necessary quality filter.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-01-25 | MSV000081972 | MassIVE
UnknownResults of the two incidence screenings in the National Lung Screening Trial.
Not available
S-EPMC4307922 | biostudies-literature
UnknownThe National Lung Screening Trial: overview and study design.
Not available
S-EPMC3009383 | biostudies-literature
GenomicsEHMT1 and EHMT2 inhibition induce fetal hemoglobin expression [ChIP-seq]
Using UNC0638 and genetic assays to inhibit EHMT1/2 and derepress fetal hemoglobin in adult hematopoietic cells. ChIP-seq for 2 histone modifications and total H3 (for quantitative normalization) in biological triplicates of cord blood, adult bone marrow, and UNC0638-treated adult bone marrow.
ORGANISM(S): Homo sapiens 
2015-11-02 | E-GEOD-69516 | biostudies-arrayexpress
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