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GenomicsGenomic binding profile of TAL1 in human Endothelial Colony-Forming Cells
Endothelial colony-forming cells (ECFCs) have been reported as promising cells for regenerative medicine thanks to their angiorepair properties. Transcription factors are primary determinants of the functional capacity of the cells and TAL1 has been shown as a critical regulator of endothelial linea...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-44442 | biostudies-arrayexpress
GenomicsComparative analysis of TAL1 binding in TSA-treated versus non-treated Endothelial Colony Forming Cells (ECFCs)
Endothelial progenitors represent one of the most promising cell-based strategies for vascular repair of ischemic tissue damage, including limb ischemia, myocardial infarction and stroke. We have shown that the transcription factor TAL1 regulates a transcription program that drives the migration and...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-53423 | biostudies-arrayexpress
TranscriptomicsshRNA mediated knock-down of Tal1 in human Endothelial Colony Forming Cells (ECFCs)
Endothelial colony-forming cells (ECFCs) have been reported as promising cells for regenerative medicine thanks to their angiorepair properties. Transcription factors are primary determinants of the functional capacity of the cells and TAL1 has been shown as a critical regulator of endothelial linea...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-44444 | biostudies-arrayexpress
GenomicsDifferential genomic targeting of the transcription factor TAL1 in alternate hematopoietic lineages
TAL1/SCL is a master regulator of hematopoiesis whose expression promotes opposite outcomes depending on the cell type - differentiation in the erythroid lineage or oncogenesis in the T-cell lineage. Here we used a combination of ChIP-sequencing and gene expression profiling to compare the function ...
ORGANISM(S): Homo sapiens 
2010-10-30 | E-GEOD-25000 | biostudies-arrayexpress
UnknownDifferential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages.
Not available
S-EPMC3034015 | biostudies-literature
UnknownEpigenetic Activation of Pro-angiogenic Signaling Pathways in Human Endothelial Progenitors Increases Vasculogenesis.
Not available
S-EPMC5830028 | biostudies-literature
UnknownCorrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.
Not available
S-EPMC6478836 | biostudies-literature
UnknownEpigenetic evolution and lineage histories of chronic lymphocytic leukaemia.
Not available
S-EPMC6533116 | biostudies-literature
UnknownDual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.
Not available
S-EPMC8380471 | biostudies-literature
UnknownThe molecular origin and taxonomy of mucinous ovarian carcinoma.
Not available
S-EPMC6718426 | biostudies-literature
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