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TranscriptomicsA gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK.
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease consisting of emphysema, small airway obstruction, and/or chronic bronchitis that results in significant loss of lung function over time. METHODS: In order to gain insights into the molecular pathways underlying prog...
ORGANISM(S): Homo sapiens 
2012-09-11 | E-GEOD-27597 | biostudies-arrayexpress
TranscriptomicsWhole-genome gene expression profiles of non-tumorous human lung tissues: UBC set
We profiled genome-wide gene expression in non-tumorous human lung tissues. The overall goal of this project is to improve our molecular understanding of various lung diseases including lung cancer and chronic obstructive pulmonary disease (COPD). The samples from the University of British Columbia ...
ORGANISM(S): Homo sapiens 
2012-06-10 | E-GEOD-23529 | biostudies-arrayexpress
TranscriptomicsWhole-genome gene expression profiles of non-tumorous human lung tissues: Laval set
We profiled genome-wide gene expression in non-tumorous human lung tissues. The overall goal of this project is to improve our molecular understanding of various lung diseases including lung cancer and chronic obstructive pulmonary disease (COPD). Lung specimens were obtained from patients undergoin...
ORGANISM(S): Homo sapiens 
2012-06-10 | E-GEOD-23352 | biostudies-arrayexpress
TranscriptomicsWhole-genome gene expression profiles of non-tumorous human lung tissues: GRNG set
We profiled genome-wide gene expression in non-tumorous human lung tissues. The overall goal of this project is to improve our molecular understanding of various lung diseases including lung cancer and chronic obstructive pulmonary disease (COPD). Lung specimens were obtained from patients with a va...
ORGANISM(S): Homo sapiens 
2012-06-10 | E-GEOD-23545 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression associated with emphysematous lung destruction
Background: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by varying degrees of emphysematous lung destruction and small airway disease, each with distinct effects on clinical outcomes. There is little known about how microRNAs contribute specifically to the e...
ORGANISM(S): Homo sapiens 
2013-12-31 | E-GEOD-49881 | biostudies-arrayexpress
TranscriptomicsWhole-genome gene expression profiles of non-tumorous human lung tissues
This SuperSeries is composed of the following subset Series: GSE23352: Whole-genome gene expression profiles of non-tumorous human lung tissues: Laval set GSE23529: Whole-genome gene expression profiles of non-tumorous human lung tissues: UBC set GSE23545: Whole-genome gene expression profiles of no...
ORGANISM(S): Homo sapiens 
2012-06-10 | E-GEOD-23546 | biostudies-arrayexpress
UnknownRegulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM.
Not available
S-EPMC8307656 | biostudies-literature
UnknownHSF2BP negatively regulates homologous recombination in DNA interstrand crosslink repair.
Not available
S-EPMC7049687 | biostudies-literature
UnknownIdentification of TMPRSS2 as a Susceptibility Gene for Severe 2009 Pandemic A(H1N1) Influenza and A(H7N9) Influenza.
Not available
S-EPMC7107393 | biostudies-literature
ProteomicsFibroblast-derived osteoglycin promotes epithelial cell repair
There is an increasing need for pharmacological treatments that target defective epithelial repair in chronic diseases, such as chronic obstructive pulmonary disease. The mesenchymal niche plays a major regulatory role in guiding epithelial progenitor cell activation during repair. We persuaded that...
ORGANISM(S): Homo sapiens (Human) 
2025-04-15 | PXD053766 | Pride
Proteomics Epithial cells Ostyglycin Copd 
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